Evidence map›Paper›PMID 31625250›Full record

ArticleNeurogastroenterology and motility2020

Rhythmic calcium transients in smooth muscle cells of the mouse internal anal sphincter.

Caroline A Cobine, Karen I Hannigan, Megan McMahon, Emer P Ni Bhraonain, Salah A Baker, Kathleen D Keef

Open access · greenAbstract read
In one paragraph

Article in Neurogastroenterology and motility, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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  5. CaPhysiological reviews · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Caroline A CobineDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, USA.ORCID 0000-0002-2871-3825
Karen I HanniganDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, USA.
Megan McMahonDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, USA.
Emer P Ni BhraonainDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, USA.
Salah A BakerDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, USA.ORCID 0000-0002-1514-6876
Kathleen D KeefDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, NV, USA.
University of Nevada, Reno · US

Funding

Control of motility in the internal anal sphincterR01DK078736 · NIDDK · UNIVERSITY OF NEVADA RENO · PI KEEF, KATHLEEN D · 2010 to 2019
$3.4M
NIDDK NIH HHS R01 DK078736
6 · The paper itself

Abstract

backgroundThe internal anal sphincter (IAS) exhibits slow waves (SWs) and tone that are dependent upon L-type Ca

methodsCa KEY

resultsCa CONCLUSIONS & INFERENCES: The similarities in spatiotemporal and pharmacological properties of CTs and SWs suggest that SW gives rise to CTs while muscle stretch is not required. Elevated relative basal Ca

Indexed as

Anal CanalAnimalsCalciumCalcium Channels, L-TypeCalcium SignalingFemaleMaleMiceMice, Inbred C57BLMuscle ContractionMyocytes, Smooth MuscleCalciumCalcium Channels, L-Typegastrointestinalinterstitial cells of Cajalpacemakerslow wavetone

Identifiers

PMID31625250
PMCPMC7047590
OpenAlexW2980727056

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.