Evidence map›Paper›PMID 31625188›Full record

ArticleThe EMBO journal2019

The Wnt/Ca

Jessica Y Vargas, Frida Loria, Yuan-Ju Wu, Gonzalo Córdova, Takashi Nonaka, Sebastien Bellow, Sylvie Syan, Masato Hasegawa, Geeske M van Woerden, Capucine Trollet and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in The EMBO journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 1 synthesis or guideline pooled it, 124 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Building the bridges: molecular mechanisms of tunneling nanotube formation.Cellular and molecular life sciences : CMLS · 2026
    Review
  5. Review
  6. ImpairedNature communications · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Beyond synapses: cytoplasmic connections in brain function and evolution.Biological reviews of the Cambridge Philosophical Society · 2025
    Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Jessica Y VargasUnité de Trafic Membranaire et Pathogénèse, Département de Biologie Cellulaire et de l'Infection, Institut Pasteur, Paris, France.
Frida LoriaUnité de Trafic Membranaire et Pathogénèse, Département de Biologie Cellulaire et de l'Infection, Institut Pasteur, Paris, France.
Yuan-Ju WuUnité de Trafic Membranaire et Pathogénèse, Département de Biologie Cellulaire et de l'Infection, Institut Pasteur, Paris, France.
Gonzalo CórdovaInstitut National de la Santé et de la Recherche Médicale, Association Institut de Myologie, Centre de Recherche en Myologie, UMRS974, Sorbonne Université, Paris, France.
Takashi NonakaDepartment of Dementia and Higher Brain Function, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.ORCID 0000-0002-0830-9403
Sebastien BellowBioAxial, Paris, France.
Sylvie SyanUnité de Trafic Membranaire et Pathogénèse, Département de Biologie Cellulaire et de l'Infection, Institut Pasteur, Paris, France.
Masato HasegawaDepartment of Dementia and Higher Brain Function, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Geeske M van WoerdenDepartment of Neuroscience, Erasmus Medical Center, Rotterdam, The Netherlands.
Capucine TrolletInstitut National de la Santé et de la Recherche Médicale, Association Institut de Myologie, Centre de Recherche en Myologie, UMRS974, Sorbonne Université, Paris, France.
Chiara ZurzoloUnité de Trafic Membranaire et Pathogénèse, Département de Biologie Cellulaire et de l'Infection, Institut Pasteur, Paris, France.ORCID 0000-0001-6048-6602
Institut Pasteur · FRInserm · FRTokyo Metropolitan Institute of Medical Science · JPErasmus MC · NL

Funding

Agence Nationale de la Recherche (ANR) ANR-16-CE16-0019-01AMED JP14533254Association France Alzheimer (French Alzheimer's Association) AAPSM2017#1674Brain Science Foundation (BSF)EC|H2020|H2020 Priority Excellent Science|H2020 Marie Skłodowska-Curie Actions (MSCA) EU project 702465 - NEUROTUNNEC|H2020|H2020 Priority Excellent Science|H2020 Marie Skłodowska-Curie Actions (MSCA) EU project 713366 - InterTalentumE-Rare/ERA-Net (SIRD)Fondation pour la Recherche Médicale (FRM) FRM-2016-DEQ20160334896Fondation Vaincre Alzheimer FR-16020MEXT JP26117005MEXT|JST|Core Research for Evolutional Science and Technology (CREST) JP18071300Pasteur-Roux-Cantarini
6 · The paper itself

Abstract

Tunneling nanotubes (TNTs) are actin-based transient tubular connections that allow direct communication between distant cells. TNTs play an important role in several physiological (development, immunity, and tissue regeneration) and pathological (cancer, neurodegeneration, and pathogens transmission) processes. Here, we report that the Wnt/Ca

Indexed as

Cell CommunicationActinsAnimalsCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Calcium SignalingCell MembraneCells, CulturedMiceMice, Inbred C57BLMice, KnockoutNanotubesNeuronsSignal TransductionWnt ProteinsActinsCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Wnt ProteinsCaMKIIintercellular communicationtunneling nanotubesWnt pathwayα-synuclein

Identifiers

PMID31625188
PMCPMC6885744
OpenAlexW2980481606

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.