Evidence map›Paper›PMID 31624951›Full record

Trial reportEuropean journal of applied physiology2019

One week of magnesium supplementation lowers IL-6, muscle soreness and increases post-exercise blood glucose in response to downhill running.

Charles James Steward, Yue Zhou, Gary Keane, Matthew David Cook, Yunyi Liu, Tom Cullen

Open access · greenAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Charles James StewardDepartment of Exercise Physiology, Beijing Sport University, Beijing, 100084, China.
Yue ZhouDepartment of Exercise Physiology, Beijing Sport University, Beijing, 100084, China.
Gary KeaneSchool of Sport and Exercise Science, University of Worcester, Henwick Grove, Worcester, WR2 6AJ, UK.
Matthew David CookSchool of Sport and Exercise Science, University of Worcester, Henwick Grove, Worcester, WR2 6AJ, UK.
Yunyi LiuDepartment of Exercise Physiology, Beijing Sport University, Beijing, 100084, China.
Tom CullenSchool of Sport and Exercise Science, University of Worcester, Henwick Grove, Worcester, WR2 6AJ, UK. ad0189@coventry.ac.uk.ORCID http://orcid.org/0000-0002-9058-6716
University of Worcester · GBBeijing Sport University · CNCoventry University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMagnesium supplementation modulates glucose metabolism and inflammation, which could influence exercise performance and recovery. This study investigated the effect of magnesium intake on physiological responses and performance during eccentric exercise and recovery.

methodsNine male recreational runners completed a counterbalanced, double-blind, placebo-controlled, cross-over study, registered at ClinicalTrial.gov. Participants consumed low magnesium diets and were supplemented with 500 mg/day of magnesium (SUP) or placebo (CON) for 7 days prior to a 10 km downhill (- 10%) running time trial (TT), separated by a 2-week washout period. At baseline and 24 h post-TT, maximal muscle force was measured. Interleukin-6 (IL-6), soluble interleukin-6 receptor (sIL-6R) and creatine kinase (CK) were measured at rest, 0 h, 1 h and 24 h post-TT. Muscle soreness was measured at the previous times plus 48 h and 72 h post. Glucose and lactate were measured during the TT.

resultsThe main effect of condition was detected for IL-6 (SUP: 1.36 ± 0.66 vs CON: 2.06 ± 1.14 pg/ml) (P < 0.05, η

conclusionMagnesium supplementation reduced the IL-6 response, enhanced recovery of blood glucose, and muscle soreness after strenuous exercise, but did not improve performance or functional measures of recovery.

Indexed as

AdultBlood GlucoseCreatine KinaseCross-Over StudiesDietary SupplementsDouble-Blind MethodExerciseHumansInflammationInterleukin-6MagnesiumMaleMuscle, SkeletalMyalgiaReceptors, Interleukin-6RunningBlood GlucoseCreatine KinaseInterleukin-6MagnesiumReceptors, Interleukin-6ExerciseGlucoseInterleukin-6MagnesiumMuscle sorenessRecovery

Identifiers

PMID31624951
OpenAlexW2981276463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.