ArticleBrain structure & function2019
TMS reveals inhibitory extrastriate cortico-cortical feedback modulation of V1 activity in humans.
Article in Brain structure & function, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Advances in magnetic field approaches for non-invasive targeting neuromodulation.Frontiers in human neuroscience · 2025Review
- cTBS over ventral cortex enhances depth perception.Frontiers in neuroscience · 2024Article
- Suppression of top-down influence decreases both behavioral and V1 neuronal response sensitivity to stimulus orientations in cats.Frontiers in behavioral neuroscience · 2023Article
- Effects of top-down influence suppression on behavioral and V1 neuronal contrast sensitivity functions in cats.iScience · 2022Article
- Precise Modulation Strategies for Transcranial Magnetic Stimulation: Advances and Future Directions.Neuroscience bulletin · 2021Review
- Suppression of top-down influence decreases neuronal excitability and contrast sensitivity in the V1 cortex of cat.Scientific reports · 2021Article
- Reply: Inhibition between human brain areas or methodological artefact?Brain : a journal of neurology · 2020Article
- Anodal transcranial direct current stimulation reduces collinear lateral inhibition in normal peripheral vision.PloS one · 2020Article
- Characterization of Feedback Neurons in the High-Level Visual Cortical Areas That Project Directly to the Primary Visual Cortex in the Cat.Frontiers in neuroanatomy · 2020Article
- Repetitive Transcranial Magnetic Stimulation for Dysesthesia Caused by Subacute Myelo-Optico-Neuropathy: A Case Report.Case reports in neurologyArticle
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3 authors.
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Abstract
The interaction between the primary visual cortex (V1) and extrastriate visual areas provides the first building blocks in our perception of the world. V2, in particular, seems to play a crucial role in shaping contextual modulation information through feedback projections to V1. However, whether this feedback is inhibitory or excitatory is still unclear. In order to test the nature of V2 feedback to V1, we used neuronavigation-guided offline inhibitory transcranial magnetic stimulation (TMS) on V2 before testing participants on collinear facilitation, a contrast detection task with lateral masking. This contextual modulation task is thought to rely on horizontal connections in V1 and possibly extrastriate feedback. Results showed that when inhibitory TMS was delivered over V2, contrast thresholds decreased for targets presented in the contralateral hemifield, consistent with the retinotopic mapping of this area, while having no effect for targets presented in the ipsilateral hemifield or after control (CZ) stimulation. These results suggest that feedback from V2 to V1 during contextual modulation is mostly inhibitory, corroborating recent observations in monkey electrophysiology and extending this mechanism to human visual system. Moreover, we provide for the first time direct evidence of the involvement of extrastriate visual areas in collinear facilitation.
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