Evidence map›Paper›PMID 31624869›Full record

ArticleActa neuropathologica2019

C9orf72-specific phenomena associated with frontotemporal dementia and gastrointestinal symptoms in the absence of TDP-43 aggregation.

Paul J Sampognaro, Sarat C Vatsavayai, Celica G Cosme, Ji-Hye L Hwang, Amber Nolan, Eric J Huang, William W Seeley, Mary G De May

Abstract readCase ReportsLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta neuropathologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paul J SampognaroDepartment of Neurology, University of California, San Francisco, Box 1207, San Francisco, USA.
Sarat C VatsavayaiDepartment of Neurology, University of California, San Francisco, Box 1207, San Francisco, USA.
Celica G CosmeDepartment of Neurology, University of California, San Francisco, Box 1207, San Francisco, USA.
Ji-Hye L HwangDepartment of Neurology, University of California, San Francisco, Box 1207, San Francisco, USA.
Amber NolanDepartment of Neurology, University of California, San Francisco, Box 1207, San Francisco, USA.
Eric J HuangDepartment of Neurology, University of California, San Francisco, Box 1207, San Francisco, USA.
William W SeeleyDepartment of Neurology, University of California, San Francisco, Box 1207, San Francisco, USA. bill.seeley@ucsf.edu.ORCID 0000-0003-1410-2027
Mary G De MayDepartment of Neurology, University of California, San Francisco, Box 1207, San Francisco, USA.

Funding

TDP-43 Loss-of-Function: Biology to BiomarkersP01AG019724 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Jennifer Merrilees · 2002 to 2026
$67.2M
Research Education ComponentP30AG062422 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Serggio Carlo Lanata · 2019 to 2026
$36.9M
PrPSc SPECIFIC INTERACTION WITH NOVEL PrP-Fc FUSION PROTEINSP50AG023501 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MILLER, BRUCE L · 2004 to 2018
$27.1M
NIA NIH HHS P01 AG019724NIA NIH HHS P30 AG062422NIA NIH HHS P50 AG023501
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedC9orf72 ProteinDNA-Binding ProteinsDNA Repeat ExpansionFatal OutcomeFemaleFrontotemporal DementiaGastrointestinal DiseasesHumansPhenotypeProtein Aggregation, PathologicalC9orf72 ProteinC9orf72 protein, humanDNA-Binding ProteinsTARDBP protein, human

Identifiers

PMID31624869
PMCPMC6858587

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.