Evidence map›Paper›PMID 31624862›Full record

ArticleImmunogenetics2020

Nomenclature report 2019: major histocompatibility complex genes and alleles of Great and Small Ape and Old and New World monkey species.

Natasja G de Groot, Nel Otting, Giuseppe Maccari, James Robinson, John A Hammond, Antoine Blancher, Bernard A P Lafont, Lisbeth A Guethlein, Emily E Wroblewski, Steven G E Marsh and 6 more

Erratum issuedAbstract readDataset
PubMed Publisher
In one paragraph

Article in Immunogenetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 35 citations in OpenAlex.

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  14. The HLA A03 Supertype and SeveralJournal of virology · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 6 countries.

Natasja G de GrootDepartment of Comparative Genetics and Refinement, Biomedical Primate Research Centre, Lange Kleiweg 161, 2288 GJ, Rijswijk, The Netherlands. groot@bprc.nl.
Nel OttingDepartment of Comparative Genetics and Refinement, Biomedical Primate Research Centre, Lange Kleiweg 161, 2288 GJ, Rijswijk, The Netherlands.
Giuseppe MaccariThe Pirbright Institute, Pirbright, Woking, Surrey, UK.
James RobinsonAnthony Nolan Research Institute, Royal Free Hospital, Pond Street, Hampstead, London, NW3 2QG, UK.
John A HammondThe Pirbright Institute, Pirbright, Woking, Surrey, UK.
Antoine BlancherCentre de Physiopathologie Toulouse-Purpan (CPTP), Université de Toulouse, Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (Inserm), Université Paul Sabatier (UPS), 31000, Toulouse, France.
Bernard A P LafontViral Immunology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Lisbeth A GuethleinDepartment of Structural Biology and Department of Microbiology and Immunology, Stanford University, Stanford, CA, 94305, USA.
Emily E WroblewskiDepartment of Anthropology, Washington University, St Louis, MO, 63130, USA.
Steven G E MarshAnthony Nolan Research Institute, Royal Free Hospital, Pond Street, Hampstead, London, NW3 2QG, UK.
Takashi ShiinaDepartment of Molecular Life Science, Division of Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, Hiratsuka-shi, Kanagawa, Japan.
Lutz WalterPrimate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research, 37077, Göttingen, Germany.
Linda VigilantMax Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103, Leipzig, Germany.
Peter ParhamDepartment of Structural Biology and Department of Microbiology and Immunology, Stanford University, Stanford, CA, 94305, USA.
David H O'ConnorDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, 53711, USA.
Ronald E BontropDepartment of Comparative Genetics and Refinement, Biomedical Primate Research Centre, Lange Kleiweg 161, 2288 GJ, Rijswijk, The Netherlands.
Biomedical Primate Research Centre · NLStanford University · USThe Royal Free Hospital · GBCentre National de la Recherche Scientifique · FRGerman Primate Center · DEMax Planck Institute for Evolutionary Anthropology · DENational Institutes of Health · USThe Pirbright Institute · GBTokai University · JPUniversity College London · GBUniversity of Wisconsin–Madison · USWashington University in St. Louis · US

Funding

Biotechnology and Biological Sciences Research Council BB/M011488/1Biotechnology and Biological Sciences Research Council BBS/E/I/00001710Biotechnology and Biological Sciences Research Council BBS/E/I/00007030Biotechnology and Biological Sciences Research Council BBS/E/I/00007038NIAID NIH HHS HHSN272201600007C
6 · The paper itself

Abstract

The major histocompatibility complex (MHC) is central to the innate and adaptive immune responses of jawed vertebrates. Characteristic of the MHC are high gene density, gene copy number variation, and allelic polymorphism. Because apes and monkeys are the closest living relatives of humans, the MHCs of these non-human primates (NHP) are studied in depth in the context of evolution, biomedicine, and conservation biology. The Immuno Polymorphism Database (IPD)-MHC NHP Database (IPD-MHC NHP), which curates MHC data of great and small apes, as well as Old and New World monkeys, has been upgraded. The curators of the database are responsible for providing official designations for newly discovered alleles. This nomenclature report updates the 2012 report, and summarizes important nomenclature issues and relevant novel features of the IPD-MHC NHP Database.

Indexed as

Databases, GeneticAllelesAnimalsCercopithecidaeHominidaeMajor Histocompatibility ComplexPhylogenyPlatyrrhiniPolymorphism, GeneticPrimatesTerminology as TopicDatabaseIPDMHCNHPNomenclature

Identifiers

PMID31624862
OpenAlexW2980379275

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.