ArticleScientific reports2019
Metabolomics of Eothenomys miletus from five Hengduan Mountains locations in summer.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Characteristics comparative of gut microbiota in four small mammal species co-occurring in the Hengduan Mountains: differences in environmental adaptation strategies between alien and endemic species.BMC microbiology · 2026Article
- Effects of Cold Exposure on Energy Metabolism and Oxidative Stress in Two Plateau Rodents.Integrative organismal biology (Oxford, England) · 2026Article
- Genome assembly of an endemic butterfly (Minois Aurata) shed light on the genetic mechanisms underlying ecological adaptation to arid valley habitat.BMC genomics · 2024Article
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3 authors.
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Abstract
Climatic characteristics of Hengduan Mountains region were diverse, and Eothenomys miletus was a native species throughout this region. To investigate adaptive strategies of E. miletus to environmental factors in different locations in this region, five locations were selected, including Deqin (DQ), Xianggelila (XGLL), Lijiang (LJ), Jianchuan (JC) and Ailaoshan (ALS). Then, body mass, visceral organ masses, and serum and liver metabolomes of E. miletus from each location were examined. The results showed that body mass was significantly different among these five sites. Liver mass was lower in ALS than in other locations. PLS-DA analysis, metabolite tree maps and heat maps of serum and liver metabolites showed that samples from DQ and XGLL clustered together, as did the samples from LJ, JC and ALS. Serum concentrations of lipid and amino acid metabolites, concentrations of TCA cycle intermediates, lipid metabolites and amino acid metabolites in livers from DQ and XGLL were higher than those from other three regions. However, the concentrations of glycolytic metabolites were lower in DQ and XGLL. All these results indicated that E. miletus adapts to changes in environmental temperature and altitude of this region by adjusting body mass and serum and liver metabolite concentrations.
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