ArticleThe ISME journal2020
Archaeal nitrification is constrained by copper complexation with organic matter in municipal wastewater treatment plants.
Article in The ISME journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 101 citations in OpenAlex.
- Isolation of genome-predicted Caldatribacterium (Atribacterota) reveals pervasive microbial cultivation problem due to folate precipitation.Nature communications · 2026Article
- Copper requirements and copper toxicity as niche-defining factors in the growth of terrestrial ammonia-oxidizing archaea and bacteria.FEMS microbiology ecology · 2026Article
- Hypoosmolarity inhibits ammonia oxidation by terrestrial and freshwater Nitrosopumilaceae members.The ISME journal · 2026Article
- Seagrass-derived carbon suppresses nitrification and NISME communications · 2026Article
- Nitrifying Communities in Biological Nitrogen Removal Processes at Tropical Municipal Wastewater Treatment Plants.Microbes and environments · 2025Article
- "mSphere · 2024Article
- ComammoxApplied and environmental microbiology · 2024Article
- Phenotypic and genomic characterization ofApplied and environmental microbiology · 2024Article
- Growth of soil ammonia-oxidizing archaea on air-exposed solid surface.ISME communications · 2024Article
- Nitrification and beyond: metabolic versatility of ammonia oxidising archaea.The ISME journal · 2023Review
- Ecological Aerobic Ammonia and Methane Oxidation Involved Key Metal Compounds, Fe and Cu.Life (Basel, Switzerland) · 2022Review
- Effects of sulphur amino acids on the size and structure of microbial communities of aerobic granular sludge bioreactors.Amino acids · 2022Article
- Quantification of archaea-driven freshwater nitrification from single cell to ecosystem levels.The ISME journal · 2022Article
- Ammonia-oxidizing archaea and complete ammonia-oxidizingWater research X · 2022Review
- Variable Inhibition of Nitrous Oxide Reduction in Denitrifying Bacteria by Different Forms of Methanobactin.Applied and environmental microbiology · 2022Article
- Assessment of the Impact of Selected Industrial Wastewater on the Nitrification Process in Short-Term Tests.International journal of environmental research and public health · 2022Article
- Ammonia-oxidizing archaea possess a wide range of cellular ammonia affinities.The ISME journal · 2022Article
- Marine ammonia-oxidising archaea and bacteria occupy distinct iron and copper niches.ISME communications · 2021Article
- Revealing taxon-specific heavy metal-resistance mechanisms in denitrifying phosphorus removal sludge using genome-centric metaproteomics.Microbiome · 2021Article
- Ammonia-oxidizing archaea in biological interactions.Journal of microbiology (Seoul, Korea) · 2021Review
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Consistent with the observation that ammonia-oxidizing bacteria (AOB) outnumber ammonia-oxidizing archaea (AOA) in many eutrophic ecosystems globally, AOB typically dominate activated sludge aeration basins from municipal wastewater treatment plants (WWTPs). In this study, we demonstrate that the growth of AOA strains inoculated into sterile-filtered wastewater was inhibited significantly, in contrast to uninhibited growth of a reference AOB strain. In order to identify possible mechanisms underlying AOA-specific inhibition, we show that complex mixtures of organic compounds, such as yeast extract, were highly inhibitory to all AOA strains but not to the AOB strain. By testing individual organic compounds, we reveal strong inhibitory effects of organic compounds with high metal complexation potentials implying that the inhibitory mechanism for AOA can be explained by the reduced bioavailability of an essential metal. Our results further demonstrate that the inhibitory effect on AOA can be alleviated by copper supplementation, which we observed for pure AOA cultures in a defined medium and for AOA inoculated into nitrifying sludge. Our study offers a novel mechanistic explanation for the relatively low abundance of AOA in most WWTPs and provides a basis for modulating the composition of nitrifying communities in both engineered systems and naturally occurring environments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.