Evidence map›Paper›PMID 31624311›Full record

ArticleJournal of human hypertension2020

Morning blood pressure surge is associated with autonomic neuropathy and peripheral vascular disease in patients with diabetes.

Federica Di Gennaro, Cinzia D'Amato, Roberto Morganti, Carla Greco, Susanna Longo, Diana Corradini, Davide Lauro, Vincenza Spallone

Abstract read
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Article in Journal of human hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Federica Di Gennaro *Endocrinology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Cinzia D'Amato *Endocrinology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Roberto MorgantiEndocrinology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Carla GrecoEndocrinology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Susanna LongoEndocrinology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Diana CorradiniEndocrinology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Davide LauroEndocrinology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Vincenza SpalloneEndocrinology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy. vispa2@gmail.com.ORCID http://orcid.org/0000-0002-8905-216X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although vascular and autonomic nervous system have been involved in the regulation of morning surge in blood pressure (MBPS), data on clinical correlates of MBPS in diabetic population are scarce, in particular with regard to diabetic complications. This study was aimed at investigating predictors and correlates of MBPS in diabetes. In a cross-sectional study including 167 patients with diabetes (age 58.5 ± 11.1 years, duration 15.9 ± 12.1 years), clinical variables, diabetic and neuropathic complications, and MBPS (using 24-h ambulatory blood pressure monitoring) were measured. The upper quartile of MBPS (>30.5 mmHg) was associated with higher values of waist circumference (P = 0.027), triglycerides (P = 0.021), and Michigan Diabetic Neuropathy Score (P = 0.042), with lower HDL cholesterol (P = 0.030), and with the presence of cardiovascular autonomic neuropathy (CAN) (P = 0.016) and peripheral vascular disease (PVD) (P < 0.0001). In a logistic regression analysis, PVD (odds ratio: 10.2, P = 0.001), CAN (odds ratio: 6.09, P = 0.016), and diastolic blood pressure (BP) (odds ratio: 1.06, P = 0.022) predicted MBPS upper quartile (r

Indexed as

Diabetes MellitusDiabetic NeuropathiesHypertensionPeripheral Vascular DiseasesAgedAutonomic Nervous SystemBlood PressureBlood Pressure Monitoring, AmbulatoryCircadian RhythmCross-Sectional StudiesHumansMiddle Aged

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.