ArticleScientific reports2019
The vernalisation regulator FLOWERING LOCUS C is differentially expressed in biennial and annual Brassica napus.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Molecular integration of seasonal temperature signals in flowering time control.Nature reviews. Genetics · 2026Review
- FLC genes control flowering time to varying degrees in a Brassica napus spring cultivar.Plant molecular biology · 2026Article
- The chromatin reader MBD4 regulates temperature- and flowering-responsive transcription by recognizing histone arginine methylation.Plant communications · 2026Article
- Pangenomic structural variant patterns reflect evolutionary diversification in Brassica napus.Genome biology · 2025Article
- All roads lead to Rome: QTL analysis for vernalization requirement and dissection of allelic variation uncovered unexpected diversity ofFrontiers in plant science · 2025Article
- QTL mapping of flowering time inFrontiers in plant science · 2025Article
- Contribution of homoeologous exchange to domestication of polyploid Brassica.Genome biology · 2024Article
- Flowering time: From physiology, through genetics to mechanism.Plant physiology · 2024Review
- A transcriptomic time-series reveals differing trajectories during pre-floral development in the apex and leaf in winter and spring varieties of Brassica napus.Scientific reports · 2024Article
- Molecular Evaluation of the Effects ofGenes · 2024Article
- A molecular mechanism for embryonic resetting of winter memory and restoration of winter annual growth habit in wheat.Nature plants · 2024Article
- Adaptation to reductions in chilling availability using variation inFrontiers in plant science · 2024Article
- Mapping QTL for vernalization requirement identified adaptive divergence of the candidate gene Flowering Locus C in polyploid Camelina sativa.The plant genome · 2023Article
- Evolutionary Dynamics ofPlants (Basel, Switzerland) · 2023Article
- Upregulation of tandem duplicated BoFLC1 genes is associated with the non-flowering trait in Brassica oleracea var. capitata.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- The two clock proteins CCA1 and LHY activate VIN3 transcription during vernalization through the vernalization-responsive cis-element.The Plant cell · 2022Article
- Construction of a Quantitative Genomic Map, Identification and Expression Analysis of Candidate Genes for Agronomic and Disease-Related Traits inFrontiers in plant science · 2022Article
- Frequent spontaneous structural rearrangements promote rapid genome diversification in aFrontiers in plant science · 2022Article
- Transcriptomic and metabolic analyses revealed the modulatory effect of vernalization on glucosinolate metabolism in radish (Raphanus sativus L.).Scientific reports · 2021Article
- A novel deletion in FLOWERING LOCUS T modulates flowering time in winter oilseed rape.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
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5 authors.
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Abstract
Plants in temperate areas evolved vernalisation requirement to avoid pre-winter flowering. In Brassicaceae, a period of extended cold reduces the expression of the flowering inhibitor FLOWERING LOCUS C (FLC) and paves the way for the expression of downstream flowering regulators. As with all polyploid species of the Brassicaceae, the model allotetraploid Brassica napus (rapeseed, canola) is highly duplicated and carries 9 annotated copies of Bna.FLC. To investigate whether these multiple homeologs and paralogs have retained their original function in vernalisation or undergone subfunctionalisation, we compared the expression patterns of all 9 copies between vernalisation-dependent (biennial, winter type) and vernalisation-independent (annual, spring type) accessions, using RT-qPCR with copy-specific primers and RNAseq data from a diversity set. Our results show that only 3 copies - Bna.FLC.A03b, Bna.FLC.A10 and to some extent Bna.FLC.C02 - are differentially expressed between the two growth types, showing that expression of the other 6 copies does not correlate with growth type. One of those 6 copies, Bna.FLC.C03b, was not expressed at all, indicating a pseudogene, while three further copies, Bna.FLC.C03a and Bna.FLC.C09ab, did not respond to cold treatment. Sequence variation at the COOLAIR binding site of Bna.FLC.A10 was found to explain most of the variation in gene expression. However, we also found that Bna.FLC.A10 expression is not fully predictive of growth type.
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