Evidence map›Paper›PMID 31624275›Full record

Observational studyScientific reports2019

Utility of High-Sensitivity and Conventional Troponin in Patients Undergoing Transcatheter Aortic Valve Replacement: Incremental Prognostic Value to B-type Natriuretic Peptide.

Yukari Kobayashi, Juyong B Kim, Kegan J Moneghetti, Michael Fischbein, Anson Lee, Claire A Watkins, Alan C Yeung, David Liang, Mehmet O Ozen, Utkan Demirci and 3 more

Abstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Time- and dose-dependent high-sensitivity cardiac troponin-T to improve outcome prediction after TAVI: a multicenter cohort study.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  2. Article
  3. Aging · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yukari KobayashiDivision of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, United States. yukariko@stanford.edu.
Juyong B KimDivision of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, United States.
Kegan J MoneghettiDivision of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, United States.
Michael FischbeinStanford Cardiovascular Institute, Stanford, CA, United States.
Anson LeeStanford Cardiovascular Institute, Stanford, CA, United States.
Claire A WatkinsStanford Cardiovascular Institute, Stanford, CA, United States.
Alan C YeungDivision of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, United States.
David LiangDivision of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, United States.
Mehmet O OzenDivision of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, United States.
Utkan DemirciDivision of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, United States.ORCID http://orcid.org/0000-0003-2784-1590
Raffick BowenDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, United States.
William F FearonDivision of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, United States.
Francois HaddadDivision of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-sensitivity Troponin (hs-Tn) has emerged as a useful marker for patients with myocardial injury or heart failure. However, few studies have compared intermediate and hs-Tn in patients undergoing transcatheter aortic valve replacement (TAVR). Moreover, there remains uncertainty of which thresholds are the most useful for discriminating ventricular dysfunction or outcome. In this study we prospectively enrolled 105 patients with severe aortic stenosis (AS) who underwent TAVR as well as blood sampling for high-sensitivity (hs-TnI) and conventional troponin I (EXL-LOCI and RXL) assessment. Patients underwent comprehensive pre-procedure echocardiography. Ventricular dysfunction was defined using left ventricular mass index (LVMI), LV global longitudinal strain (LVGLS) and LV end-diastolic pressure. The mean age was 84.0 ± 8.7 years old and 60% were male sex with mean transaortic pressure gradient of 50.1 ± 16.0 mmHg and AVA of 0.63 ± 0.19 cm

Indexed as

Transcatheter Aortic Valve ReplacementAgedAged, 80 and overAortic Valve StenosisBiomarkersEchocardiographyFeasibility StudiesFemaleFollow-Up StudiesHumansKaplan-Meier EstimateMaleNatriuretic Peptide, BrainPreoperative PeriodPrognosisProspective StudiesBiomarkersNatriuretic Peptide, BrainTroponin I

Identifiers

PMID31624275
PMCPMC6797771

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.