Evidence map›Paper›PMID 31624108›Full record

ArticleHaematologica2020

PIEZO1 gain-of-function mutations delay reticulocyte maturation in hereditary xerocytosis.

Pedro L Moura, Bethan R Hawley, Johannes G G Dobbe, Geert J Streekstra, Minke A E Rab, Paola Bianchi, Richard van Wijk, Ashley M Toye, Timothy J Satchwell

Abstract readLetter
In one paragraph

Article in Haematologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Role of the mechanotransductor PIEZO1 in megakaryocyte differentiation.Journal of cellular and molecular medicine · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Editorial: Images from red cell.Frontiers in physiology · 2022
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. A New Hope in Spinal Degenerative Diseases: Piezo1.BioMed research international · 2021
    Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pedro L MouraSchool of Biochemistry, University of Bristol, Bristol, UK.
Bethan R HawleySchool of Biochemistry, University of Bristol, Bristol, UK.
Johannes G G DobbeAmsterdam UMC, University of Amsterdam, Department of Biomedical Engineering and Physics, Amsterdam, the Netherlands.
Geert J StreekstraAmsterdam UMC, University of Amsterdam, Department of Biomedical Engineering and Physics, Amsterdam, the Netherlands.
Minke A E RabDepartment of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
Paola BianchiUOC Ematologia, UOS Fisiopatologia delle Anemie, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.
Richard van WijkDepartment of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
Ashley M ToyeSchool of Biochemistry, University of Bristol, Bristol, UK ash.m.toye@bristol.ac.uk.
Timothy J SatchwellSchool of Biochemistry, University of Bristol, Bristol, UK t.satchwell@bristol.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BB/L014181/1Department of Health NIHR-BTRU-2015-10032
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anemia, Hemolytic, CongenitalGain of Function MutationHumansHydrops FetalisIon ChannelsReticulocytesIon ChannelsPIEZO1 protein, human

Identifiers

PMID31624108
PMCPMC7271576

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.