SynthesisBMC infectious diseases2019
Systematic review and meta-analysis of tick-borne disease risk factors in residential yards, neighborhoods, and beyond.
Synthesis in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- New insights about human tick infestation features: a systematic review and meta-analysis.Environmental science and pollution research international · 2021Pooled it
- Systematic review and meta-analysis of tick-borne disease risk factors in residential yards, neighborhoods, and beyond.BMC infectious diseases · 2019Pooled it
- Why are the ticks winning, and what can we do about it?Ticks and tick-borne diseases · 2026Review
- It takes a village: Community science informs tick encounter, pathogen, and exposure risk in North Carolina, USA.PloS one · 2026Article
- Ecological and Epidemiological Consequences of Tick-Control Interventions in Residential Neighborhoods: A Synthesis of The Tick Project.Transboundary and emerging diseases · 2026Review
- 'You adapt, and you try not to resent it': a qualitative study exploring impacts of living with ticks and barriers to adopting preventive measures in Canada.BMC public health · 2025Article
- Trends in the incidence of severe fever with thrombocytopenia syndrome in Japan: an observational study from 2013 to 2022.Scientific reports · 2025Observational
- There Goes the Neighbourhood-A Multi-City Study Reveals Ticks and Tick-Borne Pathogens Commonly Occupy Urban Green Spaces.Zoonoses and public health · 2025Article
- Ixodes scapularis density and Borrelia burgdorferi prevalence along a residential-woodland gradient in a region of emerging Lyme disease risk.Scientific reports · 2024Article
- Knowledge, protective behaviours, and perception of Lyme disease in an area of emerging risk: results from a cross-sectional survey of adults in Ottawa, Ontario.BMC public health · 2024Article
- Trending ticks: using Google Trends data to understand tickborne disease prevention.Frontiers in public health · 2024Article
- Describing the experience of livestock producers from Ohio, USA with ticks and associated diseases.One health outlook · 2023Article
- Acceptability of 4-poster deer treatment devices for community-wide tick control among residents of high Lyme disease incidence counties in Connecticut and New York, USA.Ticks and tick-borne diseases · 2023Article
- What a Tick Can Tell a Doctor: Using the Human-Biting Tick in the Clinical Management of Tick-Borne Disease.Journal of clinical medicine · 2023Article
- Rodent-targeted approaches to reduce acarological risk of human exposure to pathogen-infected Ixodes ticks.Ticks and tick-borne diseases · 2023Review
- Nucleic Acid Prevalence of ZoonoticTropical medicine and infectious disease · 2023Review
- Article
- Spatial variation in risk for tick-borne diseases in residential areas of Dutchess County, New York.PloS one · 2023Article
- Integrating tick density and park visitor behaviors to assess the risk of tick exposure in urban parks on Staten Island, New York.BMC public health · 2022Article
- Risk of tick-borne pathogen spillover into urban yards in New York City.Parasites & vectors · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundExposure to blacklegged ticks Ixodes scapularis that transmit pathogens is thought to occur peri-domestically. However, the locations where people most frequently encounter infected ticks are not well characterized, leading to mixed messages from public health officials about where risk is highest.
methodsWe conducted a systematic review and meta-analysis on spatial risk factors for tick-borne disease and tick bites in eastern North America. We examined three scales: the residential yard, the neighborhood surrounding (but not including) the yard, and outside the neighborhood. Nineteen eligible studies represented 2741 cases of tick-borne illness and 1447 tick bites. Using random effects models, we derived pooled odds ratio (OR) estimates.
resultsThe meta-analysis revealed significant disease risk factors at the scale of the yard (OR 2.60 95% CI 1.96 - 3.46), the neighborhood (OR 4.08 95% CI 2.49 - 6.68), and outside the neighborhood (OR 2.03 95% CI 1.59 - 2.59). Although significant risk exists at each scale, neighborhood scale risk factors best explained disease exposure. Analysis of variance revealed risk at the neighborhood scale was 57% greater than risk at the yard scale and 101% greater than risk outside the neighborhood.
conclusionsThis analysis emphasizes the importance of understanding and reducing tick-borne disease risk at the neighborhood scale. Risk-reducing interventions applied at each scale could be effective, but interventions applied at the neighborhood scale are most likely to protect human health.
trial registrationThe study was registered with PROSPERO: CRD42017079169 .
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.