ArticleBMC genomics2019
Genome-wide identification, expression profiles and regulatory network of MAPK cascade gene family in barley.
Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 89 citations in OpenAlex.
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- Mitogen-activated protein kinase (MAPK) gene family identification reveals GhMPK10-mediated regulation of abiotic stress tolerance through protein kinase signaling cascades in cotton.BMC plant biology · 2025Article
- Genome-wide identification and molecular characterization of the MAPK family members in sand pear (Pyrus pyrifolia).BMC genomics · 2025Article
- Genome-wide identification and unveiling the role of MAP kinase cascade genes involved in sugarcane response to abiotic stressors.BMC plant biology · 2025Article
- Comprehensive analysis and identification of the WOX gene family in Schima superba and the key gene SsuWOX1 for enhancing callus regeneration capacity.BMC plant biology · 2025Article
- Identification of MAPK Genes inInternational journal of molecular sciences · 2024Article
- Advances in genomic tools for plant breeding: harnessing DNA molecular markers, genomic selection, and genome editing.Biological research · 2024Review
- Characterization and expression profiles of the ZmLBD gene family in Zea mays.Molecular biology reports · 2024Article
- Bioinformatic Identification and Expression Analyses of the MAPK-MAP4K Gene Family Reveal a Putative Functional MAP4K10-MAP3K7/8-MAP2K1/11-MAPK3/6 Cascade in Wheat (Plants (Basel, Switzerland) · 2024Article
- Identification and expression analysis of MAPK cascade gene family in foxtail millet (Plant signaling & behavior · 2023Article
- Genome-wide identification of the mitogen-activated kinase gene family from Limonium bicolor and functional characterization of LbMAPK2 under salt stress.BMC plant biology · 2023Article
- Genome-wide identification and functional characterization of borneol dehydrogenases in Wurfbainia villosa.Planta · 2023Article
- Article
- Knockout of MITOGEN-ACTIVATED PROTEIN KINASE 3 causes barley root resistance against Fusarium graminearum.Plant physiology · 2022Article
- MAPKs trigger antiviral immunity by directly phosphorylating a rhabdovirus nucleoprotein in plants and insect vectors.The Plant cell · 2022Article
- An interolog-based barley interactome as an integration framework for immune signaling.Genetics · 2022Article
- Genome-Wide Identification and Expression of MAPK Gene Family in Cultivated Strawberry and Their Involvement in Fruit Developing and Ripening.International journal of molecular sciences · 2022Article
- Global Identification and Characterization of C2 Domain-Containing Proteins Associated with Abiotic Stress Response in Rice (International journal of molecular sciences · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundMitogen-activated protein kinase (MAPK) cascade is a conserved and universal signal transduction module in organisms. Although it has been well characterized in many plants, no systematic analysis has been conducted in barley.
resultsHere, we identified 20 MAPKs, 6 MAPKKs and 156 MAPKKKs in barley through a genome-wide search against the updated reference genome. Then, phylogenetic relationship, gene structure and conserved protein motifs organization of them were systematically analyzed and results supported the predictions. Gene duplication analysis revealed that segmental and tandem duplication events contributed to the expansion of barley MAPK cascade genes and the duplicated gene pairs were found to undergone strong purifying selection. Expression profiles of them were further investigated in different organs and under diverse abiotic stresses using the available 173 RNA-seq datasets, and then the tissue-specific and stress-responsive candidates were found. Finally, co-expression regulatory network of MAPK cascade genes was constructed by WGCNA tool, resulting in a complicated network composed of a total of 72 branches containing 46 HvMAPK cascade genes and 46 miRNAs.
conclusionThis study provides the targets for further functional study and also contribute to better understand the MAPK cascade regulatory network in barley and beyond.
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