Evidence map›Paper›PMID 31623326›Full record

ArticleInternational journal of environmental research and public health2019

Availability, Price and Affordability of Anticancer Medicines: Evidence from Two Cross-Sectional Surveys in the Jiangsu Province, China.

Yulei Zhu, Ying Wang, Xiaoluan Sun, Xin Li

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
10.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  17. Procurement of medicines to treat cancer, 2015-2020, China.Bulletin of the World Health Organization · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yulei ZhuDepartment of Health Policy, School of Health Policy and Management, Nanjing Medical University, Nanjing, Jiangsu 211166, China. zhuyulei0611@njmu.edu.cn.
Ying WangDepartment of Health Policy, School of Health Policy and Management, Nanjing Medical University, Nanjing, Jiangsu 211166, China. irene0505@njmu.edu.cn.
Xiaoluan SunDepartment of Health Policy, School of Health Policy and Management, Nanjing Medical University, Nanjing, Jiangsu 211166, China. sunxiaoluan0207@njmu.edu.cn.
Xin LiDepartment of Health Policy, School of Health Policy and Management, Nanjing Medical University, Nanjing, Jiangsu 211166, China. xinli@njmu.edu.cn.ORCID 0000-0003-3951-8061
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWith the increasing incidence of cancer, poor access to affordable anticancer medicines has been a serious public health problem in China. To help address this issue, we assessed the availability, price and affordability of pharmacotherapy for cancer in public hospitals in the Jiangsu Province, China.

methodsIn 2012 and 2016, anticancer medicine availability and price information in the capital and five other cities was collected. A total of six cancer care hospitals, 26 tertiary general hospitals and 28 secondary general hospitals were sampled, using an adaptation of the World Health Organization/Health Action International methodology. Data was collected for the anticancer medicines in stock at the time of the surveys. Prices were expressed as inflation-adjusted median unit prices (MUPs). Medicine was affordable if the overall cost of all the prescribed anticancer medicines was less than 20% of the household's capacity to pay. We used generalized estimating equations to estimate the significance of differences in availability from 2012 to 2016 and the Wilcoxon rank test to estimate the significance of differences in MUPs. Multivariate logistic regression was computed to measure predictors of affordability.

resultsFrom 2012 to 2016 there was a significant decrease in the mean availability of originator brands (OBs) (from 7.79% to 5.71%,

conclusionThere were concerning decreases in the availability of anticancer medicines in 2016 from already low availability in 2012. Anticancer medicines were more affordable for the patients in high-income regions than the patients in low-income regions. Governments should consider using their bargaining power to reduce procurement prices and abolish taxes on anticancer medicines. Policy should focus on the special health insurance plan for low-income patients with cancer. The goal of drug policy should ensure that first-line generic drugs are available for cancer patients and preferentially prescribed.

Indexed as

Antineoplastic AgentsChinaCosts and Cost AnalysisCross-Sectional StudiesDrugs, EssentialHealth PolicyHealth Services AccessibilityHumansNeoplasmsPolicy MakingAntineoplastic AgentsDrugs, Essentialaffordabilityanticancer medicinesavailabilityChinaprice

Identifiers

PMID31623326
PMCPMC6801951
OpenAlexW2979284632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.