Evidence map›Paper›PMID 31623317›Full record

ReviewMolecules (Basel, Switzerland)2019

Considerations when Measuring Biocatalyst Performance.

Mafalda Dias Gomes, John M Woodley

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Advances in Machine Learning Models for Predicting Enzyme Kinetic Parameters.Journal of chemical information and modeling · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Understanding the stability of a plastic-degrading Rieske iron oxidoreductase system.Protein science : a publication of the Protein Society · 2024
    Article
  6. Combined chemoenzymatic strategy for sustainable continuous synthesis of the natural product hordenine.Green chemistry : an international journal and green chemistry resource : GC · 2022
    Article
  7. Evaluating Enzymatic Productivity-The Missing Link to Enzyme Utility.International journal of molecular sciences · 2022
    Review
  8. Review
  9. Article
  10. Immobilization of IMP-1 metallo-beta-lactamase on FeWater science and technology : a journal of the International Association on Water Pollution Research · 2022
    Article
  11. Article
  12. Applied biocatalysis beyond just buffers - from aqueous to unconventional media. Options and guidelines.Green chemistry : an international journal and green chemistry resource : GC · 2021
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mafalda Dias GomesDepartment of Chemical and Biochemical Engineering, Technical University of Denmark (DTU), DK-2800 Kgs Lyngby, Denmark. macoad@kt.dtu.dk.
John M WoodleyDepartment of Chemical and Biochemical Engineering, Technical University of Denmark (DTU), DK-2800 Kgs Lyngby, Denmark. jw@kt.dtu.dk.ORCID 0000-0002-7976-2483

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As biocatalysis matures, it becomes increasingly important to establish methods with which to measure biocatalyst performance. Such measurements are important to assess immobilization strategies, different operating modes, and reactor configurations, aside from comparing protein engineered variants and benchmarking against economic targets. While conventional measurement techniques focus on a single performance metric (such as the total turnover number), here, it is argued that three metrics (achievable product concentration, productivity, and enzyme stability) are required for an accurate assessment of scalability.

Indexed as

BiocatalysisEnzymes, ImmobilizedBiological AssayEnzyme StabilityKineticsTemperatureEnzymes, Immobilizedbiocatalysisenzyme kineticsenzyme stabilityimmobilized enzymesprocess performance metricsturnover number

Identifiers

PMID31623317
PMCPMC6804192

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.