ArticleSensors (Basel, Switzerland)2019
A Highly Selective Biosensor Based on Peptide Directly Derived from the HarmOBP7 Aldehyde Binding Site.
Article in Sensors (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 46 citations in OpenAlex.
- Enhancing the Detection of Long-Chain Aldehydes by Peptide-Based Biosensors Through Counter-Ion Exchange.Biosensors · 2026Article
- Recent Advancements in Bionic Olfactory Biosensors: Components, Applications, and Future Perspectives.Chem & bio engineering · 2025Review
- Exhaled Aldehydes and Ketones as Biomarkers of Lung Cancer and Diabetes: Review of Sensor Technologies for Early Disease Diagnosis.Biosensors · 2025Review
- Biosensors for Odor Detection: A Review.Biosensors · 2023Review
- Sound Identification Method for Gas and Coal Dust Explosions Based on MLP.Entropy (Basel, Switzerland) · 2023Article
- Human Olfactory Receptor Sensor for Odor Reconstitution.Sensors (Basel, Switzerland) · 2023Review
- Evaluation of Linkers' Influence on Peptide-Based Piezoelectric Biosensors' Sensitivity to Aldehydes in the Gas Phase.International journal of molecular sciences · 2023Article
- Adaptive Peptide Molecule as the Promising Highly-Efficient Gas-Sensor Material: In Silico Study.Sensors (Basel, Switzerland) · 2023Article
- Data-driven design of a multiplexed, peptide-sensitized transistor to detect breath VOC markers of COVID-19.Biosensors & bioelectronics · 2023Article
- Artificial Olfactory Biohybrid System: An Evolving Sense of Smell.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Review
- The Use of Terrestrial and Maritime Autonomous Vehicles in Nonintrusive Object Inspection.Sensors (Basel, Switzerland) · 2022Review
- Progress in the Development of Detection Strategies Based on Olfactory and Gustatory Biomimetic Biosensors.Biosensors · 2022Review
- Development and Assessment of Regeneration Methods for Peptide-Based QCM Biosensors in VOCs Analysis Applications.Biosensors · 2022Article
- Application and Advances in Radiographic and Novel Technologies Used for Non-Intrusive Object Inspection.Sensors (Basel, Switzerland) · 2022Review
- Viscosity Measurement Sensor: A Prototype for a Novel Medical Diagnostic Method Based on Quartz Crystal Resonator.Sensors (Basel, Switzerland) · 2021Article
- Peptides, DNA and MIPs in Gas Sensing. From the Realization of the Sensors to Sample Analysis.Sensors (Basel, Switzerland) · 2020Review
- Bio-Inspired Strategies for Improving the Selectivity and Sensitivity of Artificial Noses: A Review.Sensors (Basel, Switzerland) · 2020Review
- Sensitively and Selectively Detect Biothiols by Using Fluorescence Method and Resonance Light Scattering Technique Simultaneously.Molecules (Basel, Switzerland) · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper presents the results of research on determining the optimal length of a peptide chain to effectively bind octanal molecules. Peptides that map the aldehyde binding site in HarmOBP7 were immobilized on piezoelectric transducers. Based on computational studies, four Odorant Binding Protein-derived Peptides (OBPPs) with different sequences were selected. Molecular modelling results of ligand docking with selected peptides were correlated with experimental results. The use of low-molecular synthetic peptides, instead of the whole protein, enabled the construction OBPPs-based biosensors. This work aims at developing a biomimetic piezoelectric OBPPs sensor for selective detection of octanal. Moreover, the research is concerned with the ligand binding affinity depending on different peptides' chain lengths. The authors believe that the chain length can have a substantial influence on the type and effectiveness of peptide-ligand interaction. A confirmation of in silico investigation results is the correlation with the experimental results, which shows that the highest affinity to octanal is exhibited by the longest peptide (OBPP4 - KLLFDSLTDLKKKMSEC-NH
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.