Evidence map›Paper›PMID 31623198›Full record

ArticleMolecules (Basel, Switzerland)2019

Preparation of Ganglioside GM1 by Supercritical CO

Li Ji, Zhonghui Qiao, Xin Zhang, Xiaolei Cheng, Weiyang Wang, Fan Zhang, Yifa Zhou, Ye Yuan

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Li JiJilin Province Key Laboratory on Chemistry and Biology of Changbai Mountain Natural Drugs, School of Life Sciences, Northeast Normal University, Changchun 130024, China. jil132@nenu.edu.cn.
Zhonghui QiaoJilin Province Key Laboratory on Chemistry and Biology of Changbai Mountain Natural Drugs, School of Life Sciences, Northeast Normal University, Changchun 130024, China. qiaozh655@nenu.edu.cn.
Xin ZhangCollege of Biology and Agricultural Engineering, Jilin University, Changchun 130022, China. zhangx@jlu.edu.cn.
Xiaolei ChengJilin Province Key Laboratory on Chemistry and Biology of Changbai Mountain Natural Drugs, School of Life Sciences, Northeast Normal University, Changchun 130024, China. chengxl811@nenu.edu.cn.
Weiyang WangJilin Province Key Laboratory on Chemistry and Biology of Changbai Mountain Natural Drugs, School of Life Sciences, Northeast Normal University, Changchun 130024, China. wangwy576@nenu.edu.cn.
Fan ZhangJilin Province Key Laboratory on Chemistry and Biology of Changbai Mountain Natural Drugs, School of Life Sciences, Northeast Normal University, Changchun 130024, China. zhangf508@nenu.edu.cn.
Yifa ZhouJilin Province Key Laboratory on Chemistry and Biology of Changbai Mountain Natural Drugs, School of Life Sciences, Northeast Normal University, Changchun 130024, China. zhouyf383@nenu.edu.cn.
Ye YuanJilin Province Key Laboratory on Chemistry and Biology of Changbai Mountain Natural Drugs, School of Life Sciences, Northeast Normal University, Changchun 130024, China. yuany268@nenu.edu.cn.

Funding

Natural Science Foundation of Changchun City of China 17YJ004
6 · The paper itself

Abstract

Monosialotetrahexosylganglioside (GM1) has good activity on brain diseases and was developed to be a drug applied in clinics for neurological disorders and nerve injury. It is difficult to isolate GM1 in industry scale from the brains directly. In this work, a simple and highly efficient method with high yield was developed for the isolation, conversion, and purification of GM1 from a pig brain. Gangliosides (GLS) were first extracted by supercritical CO

Indexed as

Enzymes, ImmobilizedAcetoneAnimalsBrainCarbon DioxideFatty AcidsG(M1) GangliosideNeuraminidaseRecombinant ProteinsSubstrate SpecificitySwineAcetoneCarbon DioxideEnzymes, ImmobilizedFatty AcidsG(M1) GangliosideNeuraminidaseRecombinant ProteinsgangliosideGM1immobilizationpurificationsialidasesupercritical CO2 extraction

Identifiers

PMID31623198
PMCPMC6832980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.