Evidence map›Paper›PMID 31623147›Full record

ArticleMicroorganisms2019

CRISPR/Cas9-Mediated Gene Replacement in the Fungal Keratitis Pathogen

Jorge D Lightfoot, Kevin K Fuller

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Advances in CRISPR/Cas9-Based Gene Editing in Filamentous Fungi.Journal of fungi (Basel, Switzerland) · 2025
    Review
  5. Interaction Between Glycoside Hydrolase FsGH28c fromInternational journal of molecular sciences · 2025
    Article
  6. Review
  7. Article
  8. AMicrobiology spectrum · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Novel insights into gene therapy in the cornea.Experimental eye research · 2021
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jorge D LightfootDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA. jorge-lightfoot@ouhsc.edu.
Kevin K FullerDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA. kevin-fuller@ouhsc.edu.
University of Oklahoma Health Sciences Center · US

Funding

Fungal virulence factors during corneal infectionsR21EY028677 · NEI · DARTMOUTH-HITCHCOCK CLINIC · PI FULLER, KEVIN K., ZEGANS, MICHAEL ERIC · 2018 to 2019
$448k
NEI NIH HHS 1R21EY028677-01Research to Prevent Blindness Career Development Award
6 · The paper itself

Abstract

Fungal keratitis (FK) is a site-threatening infection of the cornea associated with ocular trauma and contact lens wear. Members of the

Indexed as

5-FOACRISPR/Cas9Fusarium petroliphilumFusarium solaniFusarium solani species complexgenome editingura3 gene

Identifiers

PMID31623147
PMCPMC6843433
OpenAlexW2980681798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.