ReviewChest2020
Sleep Pharmacotherapy for Common Sleep Disorders in Pregnancy and Lactation.
Review in Chest, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07144631 (PENS-P), which is not on this map. Cited by 30 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PENS-P: Peroneal Electrical Nerve Stimulation in Pregnancy for Restless Legs Syndrome (RLS)
Who cites it
30 citing papers in PubMed, 4 syntheses or guidelines pooled it, 81 citations in OpenAlex.
- Association between gestational hypnotic benzodiazepine receptor agonists exposure and adverse pregnancy outcomes: a systematic review and meta-analysis.Archives of women's mental health · 2025Pooled it
- The effect of physical activity on sleep disorders in pregnant people: a meta-analysis of randomized controlled trials.BMC pregnancy and childbirth · 2025Pooled it
- Sleep disturbance and its associated factors among pregnant women in Ethiopia: systematic review and meta-analysis.BMC psychiatry · 2024Pooled it
- Insomnia evaluation and treatment during peripartum: a joint position paper from the European Insomnia Network task force "Sleep and Women," the Italian Marcè Society and international experts task force for perinatal mental health.Archives of women's mental health · 2022Pooled it
- Sleep Quality in High-Risk Pregnancies: Mixed Methods Results from a Randomized Controlled Trial of a Mindfulness Training Intervention.Journal of integrative and complementary medicine · 2024Trial
- Evaluation of the Effect of Supervised Group Exercise on Self-Reported Sleep Quality in Pregnant Women with or at High Risk of Depression: A Secondary Analysis of a Randomized Controlled Trial.International journal of environmental research and public health · 2022Trial
- Association Between EAT-Lancet Diet Adherence and Sleep Quality in Lactating Women: A Cross-Sectional Analysis.Health science reports · 2026Article
- Breastfeeding Practices, Insomnia Symptoms, Anxiety, and Depression Among Lebanese Mothers: A Cross-Sectional Study.Food science & nutrition · 2026Article
- Ischemic Placental Disease and Severe Morbidity in Pregnant Patients With Sleep Disorders.JAMA network open · 2025Article
- How do you Zzz during pregnancy? A brief review of Z-drug use and management of insomnia during pregnancy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Review
- Construction and validation of a predictive model for sleep disorders among pregnant women.BMC pregnancy and childbirth · 2025Article
- Relationship between sleep pattern dysfunction with psychological stress, anxiety and depression among pregnant women.Pakistan journal of medical sciences · 2025Article
- Physical activity and sleep quality among pregnant women during the first and second trimesters are associated with mental health and adverse pregnancy outcomes.BMC women's health · 2024Article
- Subsequent maternal sleep deprivation aggravates cognitive impairment by modulating hippocampal neuroinflammatory responses and synaptic function in maternal isoflurane-exposed offspring mice.Brain and behavior · 2024Article
- Sleep quality during pregnancy following assisted reproductive technology and natural conceiving: a prospective birth cohort study.Frontiers in endocrinology · 2024Article
- The relationship between body mass index and sleep in women with risk factors for gestational diabetes mellitus.Obesity science & practice · 2023Article
- Academy of Breastfeeding Medicine Clinical Protocol #21: Breastfeeding in the Setting of Substance Use and Substance Use Disorder (Revised 2023).Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2023Article
- The effect of cognitive-behavioral counseling with or withoutSleep and biological rhythms · 2023Article
- Review
- Eye Masks and Earplugs to Improve Night Sleep Duration in Nulliparas: A Randomized Trial.Cureus · 2022Article
Corrections and comments
- Commented on by
- Commented on byResponse.2020
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Sleep disturbances are common in pregnancy, and sleep disorders may worsen or present de novo in the course of gestation. Managing a pregnant patient is complicated by the risk of teratogenicity, pharmacokinetic changes, and the dynamic nature of pregnancy. Although nonpharmacologic interventions are likely safest, they are often ineffective, and a patient is left dealing with frustrations of the sleep disturbance, as well as the negative outcomes of poor sleep in pregnancy. As with any other condition in pregnancy, management requires an understanding of pregnancy physiology, knowledge of the impact of a given condition on pregnancy or fetal and neonatal outcomes, and an ability to weigh the risk of the exposure to an untreated, or poorly treated condition, against the risk of a given drug. In partnership with the pregnant patient or couple, options for therapy should be reviewed in the context of the impact of the condition on pregnancy and offspring outcomes, while understanding that data (positive or negative) on the impact of therapy on perinatal outcomes are lacking. This article reviews the epidemiology of sleep disorders in pregnancy, general principles of prescribing in pregnancy and lactation, and safety surrounding therapeutic options in pregnancy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.