ArticlePloS one2019
The relationship between sleep quality, inappropriate medication use and frailty among older adults in aged care homes in Malaysia.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 47 citations in OpenAlex.
- Factors associated with sleep quality in community-dwelling older adults: a latent class analysis.BMC geriatrics · 2026Article
- Worldwide Prevalence of Poor Sleep Quality in Older Adults: A Systematic Review and Meta-Analysis.Iranian journal of psychiatry · 2025Review
- The association between sleep, pain and intrinsic capacity: A role for inflammation?The journal of nutrition, health & aging · 2025Article
- The Mental Health of Older People Living in Nursing Homes in Northern Portugal: A Cross-Sectional Study Protocol.Nursing reports (Pavia, Italy) · 2025Article
- Prediction of physiological status, community participation, and daily activity function to sleep quality for outpatient dynapenic older people.BMC geriatrics · 2025Article
- Sleep Quality and Medication Adherence in Older Adults: A Systematic Review.Clocks & sleep · 2024Review
- Evaluation of the Association between Medication Use and Sleep Quality among Shift Workers versus Day Workers.Sleep science (Sao Paulo, Brazil) · 2024Article
- The context of COVID-19 affected the long-term sleep quality of older adults more than SARS-CoV-2 infection.Frontiers in psychiatry · 2024Article
- Does testosterone influence the association between sleep and frailty in men: results from the European Male Aging Study.BMC geriatrics · 2023Article
- Potentially Inappropriate Medication Use among Underserved Older Latino Adults.Journal of clinical medicine · 2023Article
- Associations between Sleep Quality, Frailty, and Quality of Life among Older Adults in Community and Nursing Home Settings.International journal of environmental research and public health · 2023Article
- Overuse of medications in low- and middle-income countries: a scoping review.Bulletin of the World Health Organization · 2023Article
- Polypharmacy, potentially inappropriate medications and associated factors among older adults with hypertension in primary care.Revista brasileira de enfermagem · 2023Article
- Prevalence of Frailty and Its Standardised Assessment Tools among Malaysian Older Person: A Systematic Review.The Malaysian journal of medical sciences : MJMS · 2022Review
- Evaluation of the correlation between frailty and sleep quality among elderly patients with osteoporosis: a cross-sectional study.BMC geriatrics · 2022Article
- What Is the Relationship between Lifestyle and Frailty Status? Data from the Portuguese Multicentre Descriptive Study.Nursing reports (Pavia, Italy) · 2022Article
- Association between Physical Frailty and Sleep Quality among Saudi Older Adults: A Community-Based, Cross-Sectional Study.International journal of environmental research and public health · 2021Article
- Sleep Disturbance, Sleep Disorders and Co-Morbidities in the Care of the Older Person.Medical sciences (Basel, Switzerland) · 2021Review
- Prevalence of Drug-Related Problems and Complementary and Alternative Medicine Use in Malaysia: A Systematic Review and Meta-Analysis of 37,249 Older Adults.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Poor sleep quality is prevalent among older adults and is compounded by frailty and polypharmacy. This descriptive, cross-sectional study examines the associations between sleep quality, inappropriate medication use and frailty. The study was conducted among 151 residents of 11 aged care homes in three states in Malaysia; convenience sampling was used. Subjective sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI), and Groningen Frailty Indicator (GFI) was used to assess frailty. Medication appropriateness was assessed using Drug burden Index (DBI), Potentially Inappropriate Medications (PIMs) and Potentially Inappropriate Prescriptions (PIPs). Most of the subjects (approximately 95%) reported poor sleep quality, as measured by a cut-off of global PSQI score of ≥ 5. With a second cut-off at 10, just over half (56%) reported moderately poor sleep quality followed by 39% who had very poor sleep quality. Most (90%) denied taking medication to improve their sleep during the previous month. There was no statistically significant association between medication inappropriateness (PIMs, PIPs, DBI) and global PSQI score. However, the average number of PIM was associated significantly with sleep efficiency (a measure of the actual 'sleep to total time spent in bed) (p = 0.037). The average number of PIP was associated with subjective sleep quality (p = 0.045) and the use of sleep medications (p = 0.001), and inversely associated with sleep disturbance (0.049). Furthermore, frailty correlated significantly with poor overall sleep quality (p = 0.032). Findings support the need for medication review to identify and reduce PIMs and optimise prescriptions to improve sleep quality and hence, related health outcomes among residents of aged care homes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.