ArticlePloS one2019
Auxin driven indoleamine biosynthesis and the role of tryptophan as an inductive signal in Hypericum perforatum (L.).
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 48 citations in OpenAlex.
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- Green synthesis and characterization of Triphala SiODiscover nano · 2025Article
- Effect of Auxins on the Accumulation of Alkaloids in UngraftedMolecules (Basel, Switzerland) · 2025Article
- Enhanced In Vitro Plant Morphogenesis of Tobacco: Unveiling Indoleamine-Modulated Adaptogenic Properties of Tulsi (Plants (Basel, Switzerland) · 2024Article
- Maize heat shock proteins-prospection, validation, categorization and in silico analysis of the different ZmHSP families.Stress biology · 2023Article
- Straw Mulch Induced Indoleamines Alleviate Reproductive Depression in Cold Sensitive Hazelnut Cultivars.Plants (Basel, Switzerland) · 2023Article
- Metabolic Processes and Biological Macromolecules Defined the Positive Effects of Protein-Rich Biostimulants on Sugar Beet Plant Development.International journal of molecular sciences · 2023Article
- Effects of Coumarin on Rhizosphere Microbiome and Metabolome ofPlants (Basel, Switzerland) · 2023Article
- Plant biostimulants as natural alternatives to synthetic auxins in strawberry production: physiological and metabolic insights.Frontiers in plant science · 2023Article
- Antifungal Peptide P852 Controls Fusarium Wilt in Faba Bean (Antioxidants (Basel, Switzerland) · 2022Article
- Chitosan and Gold Nanoparticles Supplementation for Augmentation of Indole-3-Acetic Acid Production by Rhizospheric Pseudomonas aeruginosa and Plant Growth Enhancement.Current microbiology · 2022Article
- Metabolic Circuits in Sap Extracts Reflect the Effects of a Microbial Biostimulant on Maize Metabolism under Drought Conditions.Plants (Basel, Switzerland) · 2022Article
- HormonomicsDB: a novel workflow for the untargeted analysis of plant growth regulators and hormones.F1000Research · 2022Article
- Genome-wide association studies of five free amino acid levels in rice.Frontiers in plant science · 2022Article
- Ultrasonication affects the melatonin and auxin levels and the antioxidant system in potatoFrontiers in plant science · 2022Article
- A Systematic Review of Melatonin in Plants: An Example of Evolution of Literature.Frontiers in plant science · 2021Review
- Saving threatened plant species: Reintroduction of Hill's thistle (Cirsium hillii. (Canby) Fernald) to its natural habitat.PloS one · 2020Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the 60 years since Skoog and Miller first reported the chemical redirection of plant growth the underlying biochemical mechanisms are still poorly understood, with one challenge being the capacity for applied growth regulators to act indirectly or be metabolized to active phytohormones. We hypothesized that tryptophan is metabolized to auxin, melatonin or serotonin inducing organogenesis in St. John's wort (Hypericum perforatum L.). Root explants from two germplasm lines of St. John's wort with altered melatonin metabolism and wildtype were incubated with auxin or tryptophan for 24, 48 or 72 h to induce regeneration. In wildtype, tryptophan had little effect on the indoleamine pathway, and was found to promote primary growth, suggesting excess tryptophan moved quickly through various secondary metabolite pathways and protein synthesis. In lines 4 and 112 tryptophan was associated with modified morphogenesis, indoleamine and auxin levels. Incubation with tryptophan increased shoot organogenesis while incubation with auxin led to root regeneration. The established paradigm of thought views tryptophan primarily as a precursor for auxin and indoleamines, among other metabolites, and mediation of auxin action by the indoleamines as a one-way interaction. We propose that these processes run in both directions with auxin modifying indoleamine biosynthesis and the melatonin:serotonin balance contributing to its effects on plant morphogenesis, and that tryptophan also functions as an inductive signal to mediate diverse phytochemical and morphogenetic pathways.
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