ArticlePloS one2019
Dietary acid load significantly predicts 10-years survival in patients underwent coronary artery bypass grafting (CABG) surgery.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed.
- Association between enteral nutrition timing and postoperative anion gap trajectory in cardiac surgery ICU patients: a retrospective study based on the MIMIC-IV database.Journal of cardiothoracic surgery · 2026Article
- Assessing the role of dietary acid load in the development of hypertensive disorders during pregnancy: uncovering the association through prospective cohort analysis.Nutrition journal · 2024Article
- Dietary acid load in health and disease.Pflugers Archiv : European journal of physiology · 2024Review
- Higher dietary acid load is associated with hyperuricemia in Chinese adults: a case-control study.BMC endocrine disorders · 2022Article
- Dietary acid load and risk of cardiovascular disease: a prospective population-based study.BMC cardiovascular disorders · 2021Article
- Obesity Paradox of All-Cause Mortality in 4,133 Patients Treated with Coronary Revascularization.Journal of interventional cardiology · 2021Article
- Increased Acid-Producing Diet and Past Smoking Intensity Are Associated with Worse Prognoses Among Breast Cancer Survivors: A Prospective Cohort Study.Journal of clinical medicine · 2020Article
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundsNumerous studies have revealed the role of dietary acid load as a potential risk factor for cardiovascular events and blood pressure. However, its role in predicting the mortality rate in patients underwent coronary artery bypass grafting surgery (CABG) has not been reported. In the current study we aimed to evaluate the relationship of dietary acid load and cardio-metabolic risk factors with ten year survival among patients underwent CABG.
methodsThe current prospective cohort study comprises 454 patients underwent CABG. Anthropometric, clinical and biochemical measurements were performed. Dietary acid load was calculated as either potential renal acid load (PRAL) or net endogenous acid production (NEPA) using the data obtained from a semi-quantitative food frequency questionnaire (FFQ). Survival analysis was performed using Kaplan-Meier method followed by log-rank test. The association between all-cause mortality and study parameters was performed with Cox-proportional hazard model.
resultsPatients in the higher PRAL and NEAP quartiles had lower BMI and lower ejection fraction rate (P <0.05). Moreover, lower hematocrit values were observed in patients of higher PRAL quartiles. Higher PRAL scores were associated with higher mortality rate and reduced survival days (adjusted hazard ratio: 1.023 (1.00-1.04; P-value = 0.01). However, there was no relationship between NEAP and survival.
conclusionsWe revealed that high PRAL scores are positive predictors of 10-year mortality in patients underwent CABG. The results of our study suggest that maintaining an adequate acid-base balance can contribute to longevity by reducing the risk of mortality.
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