ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2020
Gastroenteritis in Men Who Have Sex With Men in Seattle, Washington, 2017-2018.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 35 citations in OpenAlex.
- Multiplex polymerase chain reaction for pathogen identification and antibiotic stewardship in human immunodeficiency virus-associated diarrhea: A retrospective study and systematic review.SAGE open medicine · 2026Review
- Determinants of Entero-Invasive and Non-Entero-Invasive Diarrheagenic Bacteria Among HIV-Positive and HIV-Negative Adults in Ghana.Medical sciences (Basel, Switzerland) · 2025Observational
- Sexually transmitted enteric infections in men who have sex with men.Clinical microbiology reviews · 2025Review
- Multiplex Polymerase Chain Reaction Panels for Gastrointestinal Infections: Current Evidence, Regulatory Hurdles, and the Way Forward.Open forum infectious diseases · 2025Article
- Can Wastewater Surveillance Enhance Genomic Tracking of Climate-Driven Pathogens?Microorganisms · 2025Review
- Risk factors and provider awareness of sexually transmitted enteric pathogens among men who have sex with men.Microbiology spectrum · 2024Article
- Article
- Challenges and Solutions to STI Control in the Era of HIV and STI Prophylaxis.Current HIV/AIDS reports · 2023Review
- Genomic reconstruction and directed interventions in a multidrug-resistant Shigellosis outbreak in Seattle, WA, USA: a genomic surveillance study.The Lancet. Infectious diseases · 2023Article
- HIV and Mediterranean Zoonoses: A Review of the Literature.Infectious disease reports · 2022Review
- A scoping review of risk factors and transmission routes associated with human giardiasis outbreaks in high-income settings.Current research in parasitology & vector-borne diseases · 2022Article
- The influence of hospitalization and HIV severity on gastrointestinal PCR panel evaluation of HIV-related acute diarrhea in New York City: a retrospective, cross-sectional study.Therapeutic advances in gastroenterology · 2022Article
- Prevalence of Gastrointestinal Pathogens Detected by Multiplex Polymerase Chain Reaction in a Prospective Cohort of Men Who Have Sex With Men Taking Human Immunodeficiency Virus Preexposure Prophylaxis-New York City, 2019-2020.Open forum infectious diseases · 2021Article
- Sexual Contact as Risk Factor for Campylobacter Infection, Denmark.Emerging infectious diseases · 2021Article
- An Unusual Case of Polymicrobial Bacteremia From Methicillin-Resistant Staphylococcus Aureus and Shigella.Cureus · 2020Article
- Sexually transmitted COVID-19.Dermatologic therapy · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundMen who have sex with men (MSM) are at risk for sexual transmission of enteric pathogens. The microbiology of gastroenteritis in MSM has not been examined since the advent of antiretroviral therapy and molecular diagnostics. Our objective was to assess the causes of gastroenteritis among MSM living with and without human immunodeficiency virus (HIV) coinfection in Seattle, Washington.
methodsWe conducted a retrospective cohort study of 235 MSM who underwent multiplex stool polymerase chain reaction (PCR) testing between 1 January 2017 and 1 June 2018. We abstracted clinical and laboratory data from electronic medical records. Parallel or reflexive culture and susceptibility testing were performed when PCR detected cultivable pathogens.
resultsAmong 235 MSM tested (268 episodes), 131 had 151 episodes with positive test results. 148 (63.0%) individuals were living with HIV. Among positive tests, 88.7% detected a bacterial pathogen, 26% a virus, and 40% a parasite. Diarrheagenic Escherichia coli (enteroaggretative, enteropathogenic), Shigella, and Campylobacter were the most commonly detected bacteria (33.1%, 30.5%, and 17.2% of positive samples, respectively). Forty-three percent of positive specimens had ≥2 pathogens. Etiologies and clinical presentations were similar between men living with and without HIV. Cultured Shigella and Campylobacter isolates were frequently resistant to multiple antibiotics.
conclusionsMSM present with gastroenteritis from varied pathogens, including some not detected by conventional stool culture. High levels of antibiotic resistance are consistent with frequent antibiotic exposure in this population and the transmission of multiresistant strains. New approaches are needed to detect, treat, and prevent enteric infections in MSM.
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Registered trials
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