Evidence map›Paper›PMID 31621639›Full record

ArticleJMIR medical informatics2019

Fast Healthcare Interoperability Resources (FHIR) as a Meta Model to Integrate Common Data Models: Development of a Tool and Quantitative Validation Study.

Emily Rose Pfaff, James Champion, Robert Louis Bradford, Marshall Clark, Hao Xu, Karamarie Fecho, Ashok Krishnamurthy, Steven Cox, Christopher G Chute, Casey Overby Taylor and 1 more

Abstract read
In one paragraph

Article in JMIR medical informatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Observational
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  19. HL7 FHIR-based tools and initiatives to support clinical research: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Emily Rose Pfaff *North Carolina Translational and Clinical Sciences Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID https://orcid.org/0000-0002-6840-9756
James ChampionNorth Carolina Translational and Clinical Sciences Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID https://orcid.org/0000-0001-5701-9931
Robert Louis BradfordNorth Carolina Translational and Clinical Sciences Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID https://orcid.org/0000-0003-0908-1428
Marshall ClarkNorth Carolina Translational and Clinical Sciences Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID https://orcid.org/0000-0001-5827-4862
Hao XuRenaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID https://orcid.org/0000-0001-6659-6511
Karamarie FechoRenaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID https://orcid.org/0000-0002-6704-9306
Ashok KrishnamurthyRenaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID https://orcid.org/0000-0002-3215-7622
Steven CoxRenaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID https://orcid.org/0000-0002-8561-4508
Christopher G ChuteJohns Hopkins University, Baltimore, MD, United States.ORCID https://orcid.org/0000-0001-5437-2545
Casey Overby TaylorJohns Hopkins University, Baltimore, MD, United States.ORCID https://orcid.org/0000-0001-9302-5968
Stan AhaltRenaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID https://orcid.org/0000-0002-8395-1279

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
Biomedical Data Translator Technical Feasibility Assessment and Architecture DesignOT3TR002019 · NCATS · JOHNS HOPKINS UNIVERSITY · PI CHUTE, CHRISTOPHER G, HAENDEL, MELISSA A · 2016 to 2019
$5.7M
Biomedical Data Translator Technical Feasibility Assessment and Architecture DesignOT3TR002026 · NCATS · INSTITUTE FOR SYSTEMS BIOLOGY · PI GLUSMAN, GWÊNLYN, HUANG, SUI · 2016 to 2019
$3.3M
Biomedical Data Translator Technical Feasibility Assessment and Architecture DesignOT3TR002020 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI AHALT, STANLEY CARLTON, TROPSHA, ALEXANDER · 2016 to 2019
$3.1M
Biomedical Data Translator Technical Feasibility Assessment and Architecture DesignOT3TR002027 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DUMONTIER, MICHEL, TATONETTI, NICHOLAS P · 2016 to 2019
$2.7M
NCATS NIH HHS OT3 TR002019NCATS NIH HHS OT3 TR002020NCATS NIH HHS OT3 TR002026NCATS NIH HHS OT3 TR002027NCATS NIH HHS UL1 TR002489
6 · The paper itself

Abstract

backgroundIn a multisite clinical research collaboration, institutions may or may not use the same common data model (CDM) to store clinical data. To overcome this challenge, we proposed to use Health Level 7's Fast Healthcare Interoperability Resources (FHIR) as a meta-CDM-a single standard to represent clinical data.

objectiveIn this study, we aimed to create an open-source application termed the Clinical Asset Mapping Program for FHIR (CAMP FHIR) to efficiently transform clinical data to FHIR for supporting source-agnostic CDM-to-FHIR mapping.

methodsMapping with CAMP FHIR involves (1) mapping each source variable to its corresponding FHIR element and (2) mapping each item in the source data's value sets to the corresponding FHIR value set item for variables with strict value sets. To date, CAMP FHIR has been used to transform 108 variables from the Informatics for Integrating Biology & the Bedside (i2b2) and Patient-Centered Outcomes Research Network data models to fields across 7 FHIR resources. It is designed to allow input from any source data model and will support additional FHIR resources in the future.

resultsWe have used CAMP FHIR to transform data on approximately 23,000 patients with asthma from our institution's i2b2 database. Data quality and integrity were validated against the origin point of the data, our enterprise clinical data warehouse.

conclusionsWe believe that CAMP FHIR can serve as an alternative to implementing new CDMs on a project-by-project basis. Moreover, the use of FHIR as a CDM could support rare data sharing opportunities, such as collaborations between academic medical centers and community hospitals. We anticipate adoption and use of CAMP FHIR to foster sharing of clinical data across institutions for downstream applications in translational research.

Indexed as

controlled vocabulariesdata sharingelectronic health recordshealth information interoperability

Identifiers

PMID31621639
PMCPMC6913576

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.