ArticleParkinsonism & related disorders2019
Objective impairment of tandem gait in Parkinson's disease patients increases with disease severity.
Article in Parkinsonism & related disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Case Report: A 1-year progression of mediolateral gait instability during tandem walking in FXTAS.Frontiers in sports and active living · 2025Article
- Tandem gait step-width increases more rapidly in more severely affected people with Parkinson's disease.Parkinsonism & related disorders · 2024Article
- Gait Declines Differentially in, and Improves Prediction of, People with Parkinson's Disease Converting to a Freezing of Gait Phenotype.Journal of Parkinson's disease · 2023Article
- Feasibility of telemedicine research visits in people with Parkinson's disease residing in medically underserved areas.Journal of clinical and translational science · 2022Article
- Concurrent Validity of Zeno Instrumented Walkway and Video-Based Gait Features in Adults With Parkinson's Disease.IEEE journal of translational engineering in health and medicine · 2022Article
- Longitudinal prediction of falls and near falls frequencies in Parkinson's disease: a prospective cohort study.Journal of neurology · 2021Article
- Transverse Strips Instead of Wearable Laser Lights Alleviate the Sequence Effect Toward a Destination in Parkinson's Disease Patients With Freezing of Gait.Frontiers in neurology · 2020Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
introductionTandem gait abnormalities have been reported to increase with advancing age, play a role in fall-prediction in Parkinson's disease, and distinguish it from atypical parkinsonism. Tandem gait has been scored based on the number of side steps off a straight line in these studies. Objective measurement of spatiotemporal tandem gait parameters in Parkinson's disease has not been previously reported.
methodsSubjects (74 Parkinson's disease and 28 controls) were enrolled after IRB approval. Those with more than 1 fall/day or a Montreal Cognitive Assessment score <10 were excluded. Subjects tandem walked ("heel to toe") on a 20 foot pressure-sensor mat. Data was collected and analyzed using PKMAS software (Protokinetics).
resultsCompared to controls, on tandem gait, Parkinson's subjects had increased step width, stride width and path width, with a slower stride velocity and an increased time spent in all phases of the gait cycle. Parkinson's subjects also applied greater pressure with each step and had greater step-to-step variability in tandem gait measures. While Hoehn & Yahr stage 1 subjects were not significantly different from controls, stage 2 and 2.5 + groups were different. Parkinson's subjects with freezing of gait also walked with a wider base compared to those without gait freezing. Tandem gait spatiotemporal parameters were not correlated with fall frequency.
conclusionsTandem gait is impaired in Parkinson's disease in a stage-dependent manner, with wider base and increased step-to-step variability, which could suggest involvement of cerebellar and mediolateral balance pathways.
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