Evidence map›Paper›PMID 31621338›Full record

ArticleOrganic letters2020

Ni-Catalyzed Suzuki-Miyaura Cross-Coupling of Aliphatic Amides on the Benchtop.

Milauni M Mehta, Timothy B Boit, Jacob E Dander, Neil K Garg

Open access · greenAbstract read
In one paragraph

Article in Organic letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 58 citations in OpenAlex.

  1. Boron in Diet and Medicine: Mechanisms of Delivery and Detection.Pharmaceuticals (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Milauni M MehtaDepartment of Chemistry and Biochemistry , University of California , Los Angeles , California 90095-1569 , United States.ORCID 0000-0002-4597-2829
Timothy B BoitDepartment of Chemistry and Biochemistry , University of California , Los Angeles , California 90095-1569 , United States.
Jacob E DanderDepartment of Chemistry and Biochemistry , University of California , Los Angeles , California 90095-1569 , United States.
Neil K GargDepartment of Chemistry and Biochemistry , University of California , Los Angeles , California 90095-1569 , United States.ORCID 0000-0002-7793-2629
University of California, Los Angeles · US

Funding

NEW DIRECTIONS IN CROSS- COUPLINGS CATALYZED BY NON- PRECIOUS METALSR01GM117016 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GARG, NEIL K · 2016 to 2019
$1.6M
Time-of-Flight Mass Spectrometer for Synthesis Supporting Biomedical ResearchS10RR025631 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HOUK, KENDALL N · 2009 to 2009
$328k
NCRR NIH HHS S10 RR025631NIGMS NIH HHS R01 GM117016
6 · The paper itself

Abstract

Suzuki-Miyaura cross-couplings of amides offer an approach to the synthesis of ketones that avoids the use of basic or pyrophoric nucleophiles. However, these reactions require glovebox manipulations, thus limiting their practicality. We report a benchtop protocol for Suzuki-Miyaura cross-couplings of aliphatic amides that utilizes a paraffin capsule containing a Ni(0) precatalyst and NHC ligand. This methodology is broad in scope, is scalable, and provides a user-friendly approach to convert aliphatic amides to alkyl-aryl ketones.

Indexed as

AmidesCatalysisKetonesMolecular StructureNickelAmidesKetonesNickel

Identifiers

PMID31621338
PMCPMC6994262
OpenAlexW2981184863

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.