Evidence map›Paper›PMID 31621316›Full record

ArticleJournal of the American Chemical Society2019

Catalase Involved in Oxidative Cyclization of the Tetracyclic Ergoline of Fungal Ergot Alkaloids.

Yongpeng Yao, Chunyan An, Declan Evans, Weiwei Liu, Wei Wang, Guangzheng Wei, Ning Ding, K N Houk, Shu-Shan Gao

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Superoxide-mediated OEngineering microbiology · 2025
    Article
  3. Article
  4. A gene regulating ergot alkaloid biosynthesis inApplied and environmental microbiology · 2024
    Article
  5. Review
  6. An unexpected role of EasDApplied microbiology and biotechnology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. A hybrid system for the overproduction of complex ergot alkaloid chanoclavine.Frontiers in bioengineering and biotechnology · 2022
    Article
  14. Review
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Yongpeng YaoState Key Laboratory of Microbial Resources , Institute of Microbiology, Chinese Academy of Sciences , Beijing 100101 , P. R. China.ORCID 0000-0002-6084-1683
Chunyan AnState Key Laboratory of Microbial Resources , Institute of Microbiology, Chinese Academy of Sciences , Beijing 100101 , P. R. China.ORCID 0000-0001-9918-5903
Declan EvansDepartment of Chemistry and Biochemistry , University of California , Los Angeles California 90095 , United States.
Weiwei LiuState Key Laboratory of Microbial Resources , Institute of Microbiology, Chinese Academy of Sciences , Beijing 100101 , P. R. China.ORCID 0000-0002-5059-9416
Wei WangState Key Laboratory of Microbial Resources , Institute of Microbiology, Chinese Academy of Sciences , Beijing 100101 , P. R. China.
Guangzheng WeiState Key Laboratory of Microbial Resources , Institute of Microbiology, Chinese Academy of Sciences , Beijing 100101 , P. R. China.
Ning DingSchool of Food Science and Technology , Jiangnan University , Wuxi , Jiangsu 214122 , P. R. China.
K N HoukDepartment of Chemistry and Biochemistry , University of California , Los Angeles California 90095 , United States.ORCID 0000-0002-8387-5261
Shu-Shan GaoState Key Laboratory of Microbial Resources , Institute of Microbiology, Chinese Academy of Sciences , Beijing 100101 , P. R. China.ORCID 0000-0001-6335-2052
Chinese Academy of Sciences · CNUniversity of California, Los Angeles · USJiangnan University · CN

Funding

CHEMISTRY BIOLOGY INTERFACE TRAINING PROGRAMT32GM008496 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MAYNARD, HEATHER D · 1993 to 2019
$6.3M
Steroselectivity of Synthetically Valuable Enzyme CatalystsR01GM124480 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HOUK, KENDALL N · 2018 to 2021
$1.1M
NIGMS NIH HHS R01 GM124480NIGMS NIH HHS T32 GM008496
6 · The paper itself

Abstract

A dedicated enzyme for the formation of the central C ring in the tetracyclic ergoline of clinically important ergot alkaloids has never been found. Herein, we report a dual role catalase (EasC), unexpectedly using O

Indexed as

Aspergillus fumigatusAspergillus nidulansCatalaseCyclizationErgolinesFree RadicalsFungal ProteinsModels, ChemicalOxidation-ReductionSaccharomyces cerevisiaeCatalaseErgolinesFree RadicalsFungal Proteins

Identifiers

PMID31621316
PMCPMC7592905
OpenAlexW2994965104

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.