Evidence map›Paper›PMID 31621112›Full record

ArticleClinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology2020

Blockade of IL-4Rα inhibits group 2 innate lymphoid cell responses in asthma patients.

Gargi Patel, Jiexue Pan, Longyun Ye, Xiaofei Shen, Daniel Rosloff, Shanti S D'Souza, Ivan Ting Hin Fung, Jocylen Celstin, Wei Sun, Poornima Sankar and 3 more

Abstract readLetter
In one paragraph

Article in Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Upregulation of IL-4 receptor signaling pathway in circulating ILC2s from asthma patients.The journal of allergy and clinical immunology. Global · 2022
    Article
  11. Article
  12. Rituximab and dupilumab improve eosinophilic granulomatosis with polyangiitis with multiple pulmonary thrombi.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2022
    Article
  13. ILCs and Allergy.Advances in experimental medicine and biology · 2022
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Group 2 innate lymphoid cells in nasal polyposis.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2021
    Review
  19. Innate Lymphoid Cells in Airway Inflammation.Advances in experimental medicine and biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gargi PatelDivision of Allergy/Immunology, Department of Medicine, Albany Medical College, Albany, NY, USA.
Jiexue PanDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY, USA.
Longyun YeDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY, USA.
Xiaofei ShenDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY, USA.
Daniel RosloffDivision of Allergy/Immunology, Department of Medicine, Albany Medical College, Albany, NY, USA.
Shanti S D'SouzaDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY, USA.
Ivan Ting Hin FungDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY, USA.
Jocylen CelstinDivision of Allergy/Immunology, Department of Medicine, Albany Medical College, Albany, NY, USA.
Wei SunDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY, USA.
Poornima SankarDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY, USA.
Yuanyue ZhangDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY, USA.
Muhammad Asghar PashaDivision of Allergy/Immunology, Department of Medicine, Albany Medical College, Albany, NY, USA.
Qi YangDivision of Allergy/Immunology, Department of Medicine, Albany Medical College, Albany, NY, USA.ORCID 0000-0002-8365-0986

Funding

Innate Lymphoid Cell AgingR01AG057782 · NIA · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI YANG, QI · 2017 to 2021
$1.7M
Development and function of inflammatory innate lymphoid cellsR01HL137813 · NHLBI · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI YANG, QI · 2018 to 2021
$1.6M
Early Innate Lymphoid Cell DevelopmentK22AI116728 · NIAID · ALBANY MEDICAL COLLEGE · PI YANG, QI · 2016 to 2017
$269k
NHLBI NIH HHS R01 HL137813NIAID NIH HHS K22 AI116728NIA NIH HHS R01 AG057782
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Immunity, CellularInterleukin-4 Receptor alpha SubunitAsthmaHumansLymphocytesIL4R protein, humanInterleukin-4 Receptor alpha Subunit

Identifiers

PMID31621112
PMCPMC6994377

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.