Evidence map›Paper›PMID 31621030›Full record

ArticleAmino acids2019

Preclinical evaluation of a

Hossein Jadvar, Kai Chen, Ryan Park, Li-Peng Yap, Ivetta Vorobyova, Steve Swenson, Francis S Markland

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Amino acids, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hossein JadvarMolecular Imaging Center, Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA. jadvar@med.usc.edu.ORCID http://orcid.org/0000-0002-9455-2484
Kai ChenMolecular Imaging Center, Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.
Ryan ParkMolecular Imaging Center, Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.
Li-Peng YapMolecular Imaging Center, Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.
Ivetta VorobyovaMolecular Imaging Center, Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.
Steve SwensonDepartment of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Francis S MarklandDepartment of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Funding

USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MYLES G COCKBURN · 1985 to 2026
$181.4M
Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
MicroPET/CT for Small Animal ImagingS10OD012371 · OD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CONTI, PETER STEPHEN · 2013 to 2013
$1.1M
Pilot Human Studies of FMAU PET in Prostate CancerR21EB017568 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JADVAR, HOSSEIN · 2015 to 2016
$433k
NCATS NIH HHS UL1 TR001855NCI NIH HHS P30 CA014089NIBIB NIH HHS R21 EB017568NIH HHS S10 OD012371
6 · The paper itself

Abstract

A novel recombinant disintegrin, vicrostatin (VCN), displays high binding affinity to a broad range of human integrins in substantial competitive biological advantage over other integrin-based antagonists. In this study, we synthesized a new

Indexed as

AnimalsCopper RadioisotopesDisintegrinsDrug Evaluation, PreclinicalHeterocyclic CompoundsHumansMaleMiceMice, NudeOrgan SpecificityPC-3 CellsPeptides, CyclicPolyethylene GlycolsPositron-Emission TomographyProstatic NeoplasmsRadiopharmaceuticalsCopper Radioisotopescyclic arginine-glycine-aspartic acid peptidediamsar chelateDisintegrinsHeterocyclic CompoundsPeptides, CyclicPolyethylene GlycolsRadiopharmaceuticalsSarcosinevicrostatin64CuAngiogenesisDisintegrinPET imagingProstate cancerVicrostatin

Identifiers

PMID31621030
PMCPMC6881555

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.