Evidence map›Paper›PMID 31620918›Full record

ArticleMikrochimica acta2019

Preparation of hollow porous molecularly imprinted and aluminum(III) doped silica nanospheres for extraction of the drugs valsartan and losartan prior to their quantitation by HPLC.

Habibeh Gholami, Mehrorang Ghaedi, Abbas Ostovan, Maryam Arabi, Ahmad Reza Bagheri

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Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Habibeh GholamiChemistry Department, Yasouj University, Yasouj, 75918-74831, Iran.
Mehrorang GhaediChemistry Department, Yasouj University, Yasouj, 75918-74831, Iran. m_ghaedi@mail.yu.ac.ir.
Abbas OstovanDepartment of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran.
Maryam ArabiChemistry Department, Yasouj University, Yasouj, 75918-74831, Iran.ORCID http://orcid.org/0000-0002-2028-9572
Ahmad Reza BagheriChemistry Department, Yasouj University, Yasouj, 75918-74831, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Water compatible hollow porous molecularly imprinted nanospheres (HP-MINs) have been prepared for specific recognition and extraction of the blood pressure regulating drugs valsartan (VAL) and losartan (LOS). All synthetic steps were performed in aqueous medium and without consumption of organic solvents. The morphology and functionality of the materials were characterized by FT-IR, FE-SEM, and TEM techniques. The adsorption and selectivity experiments demonstrate that the HP-MINs possess a high binding capacity, fast kinetics, excellent water dispersibility and remarkable selectivity for VAL and LOS. The HP-MINs were utilized for dispersive solid phase extraction of VAL and LOS prior to their determination by HPLC-UV. Main variables and their interactions on extraction yield were optimized by multivariate analysis with least amount of experiments. Under optimized conditions, the method has a linear response in the 5-2000 μg L

Indexed as

AdultAluminumCarbonChromatography, High Pressure LiquidFemaleHumansLimit of DetectionLosartanMaleMolecular ImprintingNanospheresPolymerizationPolymersPorositySilanesSilicon DioxideAluminumCarbonLosartanPolymersSilanesSilicon DioxidetetraethoxysilaneValsartanDispersive solid phase extractionExperimental design methodologyMolecularly imprinted polymersUrine analysisWater compatible

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.