Observational studyJournal of neural transmission (Vienna, Austria : 1996)2019
Vitamin D rise enhances blood perfusion in patients with multiple sclerosis.
Observational study in Journal of neural transmission (Vienna, Austria : 1996), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Vitamin D Associated with Exercise Can Be Used as a Promising Tool in Neurodegenerative Disease Protection.Molecules (Basel, Switzerland) · 2025Review
- Exploration of the Role of Vitamins in Preventing Neurodegenerative Diseases: Comprehensive Review on Preclinical and Clinical Findings.Current neuropharmacology · 2025Review
- Association between serum 25-hydroxyvitamin D3 level and cognitive impairment in older chronic kidney disease patients.Scientific reports · 2024Article
- Effect of vitamin D supplementation on cerebral blood flow in male patients with adrenoleukodystrophy.Journal of neuroscience research · 2023Article
- Vitamin D status and latitude predict brain lesions in adrenoleukodystrophy.Annals of the Child Neurology Society · 2023Article
- Physiological and Pathological Functions of Neuronal Hemoglobin: A Key Underappreciated Protein in Parkinson's Disease.International journal of molecular sciences · 2022Review
- No Vitamin D Deficiency in Patients with Parkinson's Disease.Degenerative neurological and neuromuscular disease · 2022Article
- The Role of Vitamins in Neurodegenerative Disease: An Update.Biomedicines · 2021Review
- Vitamin D and Blood Parameters.Biomolecules · 2021Observational
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Authors and funding
4 authors at 3 institutions in 1 country.
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Abstract
The chemical structure of vitamin D resembles steroids and anabolics. Following activation by enzymatic hydroxylation, vitamin D enhances numerous body functions. We determined 25-hydroxy-vitamin D, number of erythrocytes, haematocrit, mean corpuscular haemoglobin and mean corpuscular volume in 97 patients with multiple sclerosis initially and 6 months later. Patients with deficient levels of 25-hydroxyvitamin D (< 30 ng/mL) were advised to perform vitamin D supplementation and received a prescription of a vitamin D formulation. Six months later we observed a rise of 25-OH-vitamin D, as to be expected, and a modified constellation of blood parameters such as elevation of mean corpuscular haemoglobin concentration and fall of mean corpuscular volume. Mean corpuscular haemoglobin and number of erythrocytes remained stable. The haematocrit went down. We suggest that vitamin D elevation may be beneficial in disorders characterised by chronic neuroinflammation and neurodegeneration, since changes of blood perfusion parameters may enhance cellular tissue oxygenation.
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