Evidence map›Paper›PMID 31620835›Full record

ArticleIntensive care medicine2019

The urea-creatinine ratio as a novel biomarker of critical illness-associated catabolism.

Jan Gunst, Kianoush B Kashani, Greet Hermans

Registry-linked trialAbstract readEditorialComment
PubMed Publisher
In one paragraph

Article in Intensive care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07631221 (Effect of Protein Dosage on Persistent Acute Renal Failure in Critically Ill Patients.), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07631221 recruitingnot on this mapstarted 2025, after this paper: background citation

Effect of Protein Dosage on Persistent Acute Renal Failure in Critically Ill Patients.

TypeobservationalSponsorHospital Italiano de Buenos AiresRan2025 to 2026Enrolled344ConditionsAcute Kidney Failure, Critical Illness, Protein Intake, Nutritional Support
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  15. Prognostic nutritional index (PNI) correlates with survival in head and neck cancer patients more precisely than other nutritional markers - real world data.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Jan GunstClinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium. jan.gunst@kuleuven.be.ORCID http://orcid.org/0000-0003-2470-6393
Kianoush B KashaniDivision of Nephrology and Hypertension, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, 200 First Street Southwest, Rochester, MN, 55905, USA.ORCID http://orcid.org/0000-0003-2184-3683
Greet HermansMedical Intensive Care Unit, Department of General Internal Medicine and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.ORCID http://orcid.org/0000-0001-5340-1500

Funding

Fonds Wetenschappelijk Onderzoek (BE) 1805116NUniversitaire Ziekenhuizen Leuven, KU Leuven Education CouncilUniversitaire Ziekenhuizen Leuven, KU Leuven Postdoctoral research fellowship Clinical Research
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Critical IllnessUreaBiomarkersCreatinineHumansMusclesBiomarkersCreatinineUrea

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.