Evidence map›Paper›PMID 31620512›Full record

ArticleACG case reports journal2019

Hepatic Sinusoidal Obstruction Syndrome in a Patient With Multiple Myeloma Treated With CyBorD.

Tooba Tariq, John Dawdy, Sachin Goyal, Bashar Mohamad, Manmeet Singh, Milton Mutchnick, Murray Ehrinpreis

Open access · diamondAbstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Tooba TariqDepartment of Internal Medicine, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, MI.
John DawdyDepartment of Internal Medicine, Detroit Medical Center/Wayne State University, Detroit, MI.
Sachin GoyalDepartment of Gastroenterology, Detroit Medical Center/Wayne State University, Detroit, MI.
Bashar MohamadDepartment of Gastroenterology, Detroit Medical Center/Wayne State University, Detroit, MI.
Manmeet SinghDepartment of Internal Medicine, Detroit Medical Center/Wayne State University, Detroit, MI.
Milton MutchnickDepartment of Gastroenterology, Detroit Medical Center/Wayne State University, Detroit, MI.
Murray EhrinpreisDepartment of Gastroenterology, Detroit Medical Center/Wayne State University, Detroit, MI.
Detroit Medical Center · USWayne State University · USStryker (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic sinusoidal obstruction syndrome (SOS) is a life-threatening state generally occurring as a complication of conditioning regimens used for hematopoietic stem cell transplant. Hepatic SOS after a standard dose of chemotherapy in malignancies is rare, and there are only a few cases in pediatric literature. We report a 56-year-old man with multiple myeloma who experienced SOS after being initiated on chemotherapy including cyclophosphamide, dexamethasone, and bortezomib and who experienced a delay in treatment with defibrotide, because it is currently approved by the Food and Drug Administration for only patients who develop SOS after hematopoietic stem cell transplant.

Identifiers

PMID31620512
PMCPMC6722380
OpenAlexW2964979057

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.