Evidence map›Paper›PMID 31620338›Full record

ArticleWorld journal of plastic surgery2019

Extraction and Characterization of Collagen with Cost-Effective Method from Human Placenta for Biomedical Applications.

Ali Karami, Hamid Tebyanian, Reza Sayyad Soufdoost, Ebrahim Motavallian, Aref Barkhordari, Mohammad Reza Nourani

Abstract read
In one paragraph

Article in World journal of plastic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ali KaramiNanobiotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Hamid TebyanianResearch Center for Prevention of Oral and Dental Diseases, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Reza Sayyad SoufdoostImam Khomeini Clinic of Dentistry, Tehran, Iran.
Ebrahim MotavallianDepartment of General Surgery, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Aref BarkhordariNanobiotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Mohammad Reza NouraniNanobiotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCollagen is the main product in pharmaceutics and food industry with a high demand. Collagen can be extracted from several tissues such as skin, bone and tendon, etc. Collagen can be used in tissue engineering researches as a substrate of wound healing and nerve regeneration. Extraction methods of collagen are various with different purities. In this research, we aimed to extract collagen from human placenta with a modified method.

methodsThis modified approach was used for extracting of collagen from human placenta with acetic acid and NaCl treatment using different concentrations.

resultsSDS page showed three different bands that reflected two alpha-chains and one beta-chain with molecular weights of 102, 118 and 220 kDa, respectively. There was no significant difference between extracted collagen from human placenta and standard collagen in western blot analysis.

conclusionIt was concluded that human placenta can be an alternative source of collagen with high purity for biomedical applications such as tissue engineering, stem cell therapy and research.

Indexed as

CharacterizationCollagenExtractionHumaPlacenta

Identifiers

PMID31620338
PMCPMC6790260

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.