ArticleAnnals of occupational and environmental medicine2019
Relationship between triclosan exposure and thyroid hormones: the Second Korean National Environmental Health Survey (2012-2014).
Article in Annals of occupational and environmental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- The Influence of Triclosan on the Thyroid Hormone System in Humans - A Systematic Review.Frontiers in endocrinology · 2022Pooled it
- Conceptualizing the Role of the Microbiome as a Mediator and Modifier in Environmental Health Studies: A Scoping Review of Studies of Triclosan and the Microbiome.Current environmental health reports · 2024Article
- Article
- Triclosan and Its Consequences on the Reproductive, Cardiovascular and Thyroid Levels.International journal of molecular sciences · 2022Review
- Obesogens in Foods.Biomolecules · 2022Review
- Effect of Maternal Triclosan Exposure on Neonatal Thyroid-Stimulating Hormone Levels: A Cross-Sectional Study.Journal of environmental and public health · 2022Article
- Evaluation of triclosan exposures on secretion of pro-inflammatory cytokines from human immune cells.Environmental toxicology and pharmacology · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background5-chloro-2-(2,4-dichlorophenoxy)phenol (triclosan) is used as an antiseptic and is a potential endocrine-disrupting chemical that can affect thyroid hormone levels. This study evaluated the relationship between triclosan exposure and thyroid hormones.
methodsData from the second Korean National Environmental Health Survey (2012-2014) were analyzed. Triclosan exposure was evaluated using urinary triclosan concentrations and classified into 2 groups: 'below detection (< limit of detection [LOD])' vs. 'detected (≥ LOD).' Multiple linear regression analysis was conducted to determine the relationship between triclosan exposure and the serum thyroid hormone concentrations, adjusting for age, body mass index, urinary creatinine, and smoking status.
resultsWhen grouped by sex, triclosan exposure was positively associated with the serum thyroid-stimulating hormone (TSH) concentrations in females with marginal significance (β = 0.066,
conclusionsThis study is the first human study to evaluate the relationship between triclosan exposure and serum thyroid hormone concentrations in the Korean population. There was suggestive positive association between triclosan exposure and the serum TSH in females. Further studies need to evaluate the relationship between long-term exposure to low-dose triclosan and thyroid hormones.
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Registered trials
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