Evidence map›Paper›PMID 31620259›Full record

ArticleHeart views : the official journal of the Gulf Heart Association

Kounis Syndrome: A More Commonly Encountered Cause of Acute Coronary Syndrome.

Christina Rodríguez-Ruiz, Gisela Puig-Carrión, Andrea Delgado-Nieves, Angel López-Candales

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Heart views : the official journal of the Gulf Heart Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Presumed insect sting-induced Takotsubo cardiomyopathy.The journal of allergy and clinical immunology. Global · 2025
    Article
  6. Recognizing Kounis Syndrome, the Unusual Possible Culprit of Acute Coronary Syndrome: A Rare Case Report.The International journal of angiology : official publication of the International College of Angiology, Inc · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Clinical complications in envenoming byFrontiers in immunology · 2024
    Review
  12. Article
  13. Article
  14. Optimal management of coronary artery disease in cancer patients.Chronic diseases and translational medicine · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Christina Rodríguez-RuizDepartment of Internal Medicine, University of Puerto Rico School of Medicine, San Juan, Puerto Rico, USA.
Gisela Puig-CarriónCardiovascular Medicine Division, University of Puerto Rico School of Medicine, San Juan, Puerto Rico, USA.
Andrea Delgado-NievesUniversity of Puerto Rico School of Medicine, San Juan, Puerto Rico, USA.
Angel López-CandalesCardiovascular Medicine Division, University of Puerto Rico School of Medicine, San Juan, Puerto Rico, USA.
University of Puerto Rico System · PR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kounis syndrome (KS) has been defined as cardiovascular symptoms that occur secondary to allergic or hypersensitivity insults. It was thought to be a rare condition but is now being more commonly identified as the cause of acute coronary events in patients without previous history of coronary artery disease (CAD). The most identified KS cases have been provoked by medications on elderly male patients. The purpose of this case report is to describe an unusual case of KS, triggered by a food allergen in a young female patient. This case reminds us that it is important to have a high index of suspicion, particularly in MI patients presenting without previous history of CAD. In this manner, an appropriate management, considering both cardiac and allergic components of KS, can be given without further delay and progression of symptoms.

Indexed as

Acute coronary artery syndromeallergic reactionschest painhypersensitivityKounis syndrometype 2 myocardial infarctionvasospasm

Identifiers

PMID31620259
PMCPMC6791094
OpenAlexW2975591400

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.