Evidence map›Paper›PMID 31620086›Full record

ArticleFrontiers in endocrinology2019

Adipsic Diabetes Insipidus-The Challenging Combination of Polyuria and Adipsia: A Case Report and Review of Literature.

Rinkoo Dalan, Hanxin Chin, Jeremy Hoe, Abel Chen, Huiling Tan, Bernhard Otto Boehm, Karen SuiGeok Chua

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. 'Un-thirsty' hypernatremia.Endocrinology, diabetes & metabolism case reports · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Autoimmunity Related to Adipsic Hypernatremia and ROHHAD Syndrome.International journal of molecular sciences · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rinkoo DalanDepartment of Endocrinology, Tan Tock Seng Hospital, Singapore, Singapore.
Hanxin ChinDepartment of Endocrinology, Tan Tock Seng Hospital, Singapore, Singapore.
Jeremy HoeDepartment of Endocrinology, Tan Tock Seng Hospital, Singapore, Singapore.
Abel ChenDepartment of Endocrinology, Tan Tock Seng Hospital, Singapore, Singapore.
Huiling TanDepartment of Anaesthesiology, Intensive Care and Pain Medicine, Tan Tock Seng Hospital, Singapore, Singapore.
Bernhard Otto BoehmDepartment of Endocrinology, Tan Tock Seng Hospital, Singapore, Singapore.
Karen SuiGeok ChuaDepartment of Rehabilitation Medicine, Tan Tock Seng Hospital, Singapore, Singapore.
Tan Tock Seng Hospital · SGNanyang Technological University · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipsic Diabetes Insipidus is a rare hypothalamic disorder characterized by a loss of thirst in response to hypernatraemia accompanied by diabetes insipidus. These occur secondary to a congregation of defects in the homeostatic mechanisms of water balance. A 27-year old Chinese female presented with Adipsic Diabetes Insipidus after cerebral arteriovenous malformation (AVM) surgery. Initial diagnosis and management was extremely challenging. Long term management required a careful interplay between low dose vasopressin analog treatment and fluids. Detailed charts of medication and sodium balance are described in the case presentation. We performed a literature search of similarly reported cases and describe the possible pathogenesis, etiology, clinical presentation, acute and chronic management, and prognosis.

Indexed as

adipsiadiabetes insipidushypothalamus and neuroendocrinologythirst and drinkingwater balance

Identifiers

PMID31620086
PMCPMC6759785
OpenAlexW2971066254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.