Evidence map›Paper›PMID 31619783›Full record

ArticleNature2019

Brain-to-pancreas signalling axis links nicotine and diabetes.

Giuseppe Bruschetta, Sabrina Diano

Abstract readNewsComment
In one paragraph

Article in Nature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Giuseppe Bruschetta
Sabrina Diano

Funding

Mitochondrial Dynamics in VMH Neurons Control Glucose MetabolismR01DK107293 · NIDDK · YALE UNIVERSITY · PI DIANO, SABRINA · 2015 to 2022
$3.6M
Role of Peroxisome Proliferation in Leptin ResistanceR01DK097566 · NIDDK · YALE UNIVERSITY · PI DIANO, SABRINA · 2013 to 2020
$3.3M
Intracellular mechanisms of microglia activation in diet-induced obesityR01DK120321 · NIDDK · YALE UNIVERSITY · PI DIANO, SABRINA · 2018 to 2021
$3.2M
Central Prolyl Carboxypeptidase (PRCP) in the Regulation of MetabolismR01DK105571 · NIDDK · YALE UNIVERSITY · PI DIANO, SABRINA · 2016 to 2019
$1.5M
NIDDK NIH HHS R01 DK097566NIDDK NIH HHS R01 DK105571NIDDK NIH HHS R01 DK107293NIDDK NIH HHS R01 DK120321
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes MellitusNicotineBrainHumansPancreasSignal TransductionTranscription Factor 7-Like 2 ProteinNicotineTCF7L2 protein, humanTranscription Factor 7-Like 2 ProteinDiabetesMetabolismNeurosciencePhysiology

Identifiers

PMID31619783
PMCPMC7224251

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.