ArticleNature2019
Reversion after replacement of mitochondrial DNA.
Article in Nature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Emerging therapeutic strategies for mitochondrial DNA-related diseases.Cell reports. Medicine · 2026Review
- Mitochondrial Transfer: From Bench to Bedside.Circulation research · 2026Review
- The need to understand the underlying mechanisms associated with mitochondrial therapies in assisted reproduction before further clinical trials are performed.Human reproduction (Oxford, England) · 2026Review
- The nuclear and mitochondrial genomes need to tango. How is their dance synchronized during development?NAR molecular medicine · 2026Article
- Spatiotemporal Distribution and Function of Mitochondria in Oocytes.Reproductive sciences (Thousand Oaks, Calif.) · 2024Review
- Mitochondrial DNA editing with mitoARCUS.Nature metabolism · 2023Article
- Feasibility and impact of haplogroup matching for mitochondrial replacement treatment.EMBO reports · 2023Article
- Modeling mitochondrial DNA diseases: from base editing to pluripotent stem-cell-derived organoids.EMBO reports · 2023Review
- Mitochondrial DNAFrontiers in ophthalmology · 2023Article
- Reduction of mtDNA heteroplasmy in mitochondrial replacement therapy by inducing forced mitophagy.Nature biomedical engineering · 2022Article
- Cellular mechanisms of mtDNA heteroplasmy dynamics.Critical reviews in biochemistry and molecular biology · 2021Review
- Mitochondrial function in development and disease.Disease models & mechanisms · 2021Review
- Generation of somatic mitochondrial DNA-replaced cells for mitochondrial dysfunction treatment.Scientific reports · 2021Article
- Extreme heterogeneity of human mitochondrial DNA from organelles to populations.Nature reviews. Genetics · 2021Review
- Natural and Artificial Mechanisms of Mitochondrial Genome Elimination.Life (Basel, Switzerland) · 2021Review
- Mitochondrial replacement by genome transfer in human oocytes: Efficacy, concerns, and legality.Reproductive medicine and biology · 2021Review
- Therapeutic Approaches to Treat Mitochondrial Diseases: "One-Size-Fits-All" and "Precision Medicine" Strategies.Pharmaceutics · 2020Review
- MtDNA sequence features associated with 'selfish genomes' predict tissue-specific segregation and reversion.Nucleic acids research · 2020Article
- Mitochondrial Genetic Drift after Nuclear Transfer in Oocytes.International journal of molecular sciences · 2020Review
- Mitochondrial DNA heteroplasmy in disease and targeted nuclease-based therapeutic approaches.EMBO reports · 2020Review
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
31619779What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.