Evidence map›Paper›PMID 31619708›Full record

ArticleScientific reports2019

Risk Factors of Neovascular Glaucoma After 25-gauge Vitrectomy for Proliferative Diabetic Retinopathy with Vitreous Hemorrhage: A Retrospective Multicenter Study.

Kei Takayama, Hideaki Someya, Hiroshi Yokoyama, Yoshihiro Takamura, Masakazu Morioka, Seiji Sameshima, Tetsuo Ueda, Shigehiko Kitano, Maki Tashiro, Masahiko Sugimoto and 3 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

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  9. Bilateral vitrectomy in patients with proliferative diabetic retinopathy-characteristics and surgical outcomes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 1 country.

Kei TakayamaDepartment of Ophthalmology, National Defense Medical College, Tokorozawa, 3598513, Japan.
Hideaki SomeyaDepartment of Ophthalmology, National Defense Medical College, Tokorozawa, 3598513, Japan.
Hiroshi YokoyamaDepartment of Ophthalmology, Hyogo College of Medicine, Nishinomiya, 6638501, Japan.
Yoshihiro TakamuraDepartment of Ophthalmology, University of Fukui Faculty of Medical Sciences, Yoshida, 9101193, Japan.
Masakazu MoriokaDepartment of Ophthalmology, University of Fukui Faculty of Medical Sciences, Yoshida, 9101193, Japan.
Seiji SameshimaDepartment of Ophthalmology, Kagoshima University, Kagoshima, 8900046, Japan.
Tetsuo UedaDepartment of Ophthalmology, Nara Medical University, Kashihara, 6348522, Japan.
Shigehiko KitanoDiabetes Center, Tokyo Women's Medical University School of Medicine, Tokyo, 1628666, Japan.
Maki TashiroDiabetes Center, Tokyo Women's Medical University School of Medicine, Tokyo, 1628666, Japan.
Masahiko SugimotoDepartment of Ophthalmology, Mie University, Tsu, 5148507, Japan.
Mineo KondoDepartment of Ophthalmology, Mie University, Tsu, 5148507, Japan.
Taiji SakamotoDepartment of Ophthalmology, Kagoshima University, Kagoshima, 8900046, Japan.
Masaru TakeuchiDepartment of Ophthalmology, National Defense Medical College, Tokorozawa, 3598513, Japan. masatake@ndmc.ac.jp.ORCID http://orcid.org/0000-0002-4913-7089
Kagoshima University · JPMie University · JPNational Defense Medical College · JPTokyo Women's Medical University · JPUniversity of Fukui · JPHyogo Medical University · JPNara Medical University · JPNational Defense Medical College Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neovascular glaucoma (NVG) is a terminal severe complication in eyes with proliferative diabetic retinopathy (PDR), and PDR eyes with vitreous hemorrhage (VH) which undergo vitrectomy may have higher risk of postoperative NVG. The incidence and the prognostic factor of postoperative NVG after 25-gauge vitrectomy with advanced surgical options remain unclear. We retrospectively reviewed medical records of 268 eyes of 268 consecutive PDR patients with VH who underwent 25-gauge vitrectomy and 12 months follow-up at seven centers. Preoperative ocular factors (visual acuity, tractional retinal detachment, panretinal photocoagulation [PRP]), demographics and clinical factors (sex, age, diabetic duration, HbA1c, hypertension, anticoagulant medication, and kidney function), surgical procedures, and postoperative complications were compared between patients who developed postoperative NVG (9.3%) and those who did not. NVG eyes was significantly younger (P = 0.026), had shorter diabetic duration (P = 0.022), higher HbA1c (P = 0.028), absence of PRP (P = 0.039) and higher frequency of postoperative VH (P = 0.0075) than non-NVG eyes. Logistic regression analysis identified postoperative VH (P = 0.014), shorter diabetic duration (P = 0.029), and no PRP (P = 0.028) as prognostic factors for postoperative NVG. This multicenter study indicates that younger age, uncontrolled diabetes, no PRP, and postoperative VH are risk factors of post-vitrectomy NVG.

Indexed as

AdultAgedAge FactorsDiabetic RetinopathyFemaleGlaucoma, NeovascularGlycated HemoglobinHumansHypertensionLight CoagulationMaleMiddle AgedRenal Insufficiency, ChronicRetinal DetachmentRetrospective StudiesRisk FactorsGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID31619708
PMCPMC6795876
OpenAlexW2980816028

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.