Evidence map›Paper›PMID 31619501›Full record

ArticlemSphere2019

Functional Characterization of Entamoeba histolytica Argonaute Proteins Reveals a Repetitive DR-Rich Motif Region That Controls Nuclear Localization.

Hanbang Zhang, Vy Tran, Dipak Manna, Gretchen Ehrenkaufer, Upinder Singh

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Exploring virulence and stress response inMicrobiology spectrum · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hanbang ZhangDivision of Infectious Diseases, Department of Internal Medicine, Stanford University School of Medicine, Stanford, California, USA.
Vy TranDivision of Infectious Diseases, Department of Internal Medicine, Stanford University School of Medicine, Stanford, California, USA.
Dipak MannaDivision of Infectious Diseases, Department of Internal Medicine, Stanford University School of Medicine, Stanford, California, USA.
Gretchen EhrenkauferDivision of Infectious Diseases, Department of Internal Medicine, Stanford University School of Medicine, Stanford, California, USA.
Upinder SinghDivision of Infectious Diseases, Department of Internal Medicine, Stanford University School of Medicine, Stanford, California, USA usingh@stanford.edu.
Stanford University · US

Funding

Small RNA regulation of gene expression in EntamoebaR01AI121084 · NIAID · STANFORD UNIVERSITY · PI SINGH, UPINDER · 2016 to 2020
$3.1M
NIAID NIH HHS R01 AI121084
6 · The paper itself

Abstract

The RNA interference (RNAi) pathway regulates gene expression in many eukaryotic organisms. Argonaute (Ago) proteins, together with bound small RNAs (sRNAs), are key effectors that mediate gene silencing function. However, there is limited knowledge of Ago proteins and their functions in nonmodel systems. In the protozoan parasite

Indexed as

Repetitive Sequences, Nucleic AcidArgonaute ProteinsEntamoeba histolyticaGene Expression RegulationGene SilencingProtozoan ProteinsRNA-Induced Silencing ComplexRNA InterferenceRNA, Small UntranslatedStress, PhysiologicalArgonaute ProteinsProtozoan ProteinsRNA-Induced Silencing ComplexRNA, Small UntranslatedArgonaute proteinsEntamoebagene expressionRNA interferencetranscriptional regulation

Identifiers

PMID31619501
PMCPMC6796981
OpenAlexW2980957548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.