ReviewThe Journal of neuroscience : the official journal of the Society for Neuroscience2019
Advanced Circuit and Cellular Imaging Methods in Nonhuman Primates.
Review in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 39 citations in OpenAlex.
- A large-scale optogenetic neurophysiology platform for improving accessibility in non-human primate behavioral experiments.Nature communications · 2026Article
- A large-scale optogenetic neurophysiology platform for improving accessibility in non-human primate behavioral experiments.bioRxiv : the preprint server for biology · 2025Article
- A Neural Implant Design Toolbox for Nonhuman Primates.Journal of visualized experiments : JoVE · 2024Article
- The Cousa objective: a long-working distance air objective for multiphoton imaging in vivo.Nature methods · 2024Article
- Genetic Approaches for Neural Circuits Dissection in Non-human Primates.Neuroscience bulletin · 2023Review
- From static to dynamic: live observation of the support system after ischemic stroke by two photon-excited fluorescence laser-scanning microscopy.Neural regeneration research · 2023Review
- The Role of Nonhuman Primates in Neurotoxicology Research: Preclinical Models and Experimental Methods.Current protocols · 2023Article
- Genetically encoded fluorescent sensors for imaging neuronal dynamics in vivo.Journal of neurochemistry · 2023Review
- Review
- Multimodal Noninvasive Functional Neurophotonic Imaging of Murine Brain-Wide Sensory Responses.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Improving the Efficacy and Accessibility of Intracranial Viral Vector Delivery in Non-Human Primates.Pharmaceutics · 2022Article
- A versatile toolbox for studying cortical physiology in primates.Cell reports methods · 2022Article
- Optical deep-cortex exploration in behaving rhesus macaques.Nature communications · 2021Article
- Combining brain perturbation and neuroimaging in non-human primates.NeuroImage · 2021Review
- Through the looking glass: A review of cranial window technology for optical access to the brain.Journal of neuroscience methods · 2021Review
- Multi-modal artificial dura for simultaneous large-scale optical access and large-scale electrophysiology in non-human primate cortex.Journal of neural engineering · 2021Article
- Phosphorylation of GAP-43 T172 is a molecular marker of growing axons in a wide range of mammals including primates.Molecular brain · 2021Article
- Translational value of non-human primates in opioid research.Experimental neurology · 2021Review
- A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates.Journal of visualized experiments : JoVE · 2020Article
- Microsaccades in Applied Environments: Real-World Applications of Fixational Eye Movement Measurements.Journal of eye movement research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 8 institutions in 3 countries.
Funding
Abstract
Novel genetically encoded tools and advanced microscopy methods have revolutionized neural circuit analyses in insects and rodents over the last two decades. Whereas numerous technical hurdles originally barred these methodologies from success in nonhuman primates (NHPs), current research has started to overcome those barriers. In some cases, methodological advances developed with NHPs have even surpassed their precursors. One such advance includes new ultra-large imaging windows on NHP cortex, which are larger than the entire rodent brain and allow analysis unprecedented ultra-large-scale circuits. NHP imaging chambers now remain patent for periods longer than a mouse's lifespan, allowing for long-term all-optical interrogation of identified circuits and neurons over timeframes that are relevant to human cognitive development. Here we present some recent imaging advances brought forth by research teams using macaques and marmosets. These include technical developments in optogenetics; voltage-, calcium- and glutamate-sensitive dye imaging; two-photon and wide-field optical imaging; viral delivery; and genetic expression of indicators and light-activated proteins that result in the visualization of tens of thousands of identified cortical neurons in NHPs. We describe a subset of the many recent advances in circuit and cellular imaging tools in NHPs focusing here primarily on the research presented during the corresponding mini-symposium at the 2019 Society for Neuroscience annual meeting.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.