Evidence map›Paper›PMID 31618904›Full record

ReviewAnimals : an open access journal from MDPI2019

n-3 PUFA Sources (Precursor/Products): A Review of Current Knowledge on Rabbit.

María Rodríguez, Pilar G Rebollar, Simona Mattioli, Cesare Castellini

Open access · goldAbstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 48 citations in OpenAlex.

  1. Effect of Dietary Inclusion of House Cricket (Animals : an open access journal from MDPI · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Analysis of Flavor Differences BetweenFoods (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

María RodríguezDepartamento de Producción Agraria, Escuela Técnica Superior de Ingeniería Agronómica Alimentaria y de Biosistemas, Universidad Politécnica de Madrid, Ciudad Universitaria s/n, 28040 Madrid, Spain. maria_rodriguez_francisco@hotmail.com.
Pilar G RebollarDepartamento de Producción Agraria, Escuela Técnica Superior de Ingeniería Agronómica Alimentaria y de Biosistemas, Universidad Politécnica de Madrid, Ciudad Universitaria s/n, 28040 Madrid, Spain. pilar.grebollar@upm.es.ORCID 0000-0003-4418-0157
Simona MattioliDepartment of Agricultural, Environmental and Food Science, University of Perugia, Borgo XX Giugno, 74, 06121 Perugia, Italy. simona.mattioli@hotmail.it.ORCID 0000-0001-5063-6785
Cesare CastelliniDepartment of Agricultural, Environmental and Food Science, University of Perugia, Borgo XX Giugno, 74, 06121 Perugia, Italy. cesare.castellini@unipg.it.ORCID 0000-0002-6134-0901
Universidad Politécnica de Madrid · ESUniversity of Perugia · IT

Funding

Spanish Ministry of Economy and Competitiveness [Project AGL2015-65572-C2-R1]
6 · The paper itself

Abstract

This review compares the effects of different n-3 polyunsaturated fatty acid (PUFA) sources on biological activity, physiological/reproductive endpoints, and health implications with a special emphasis on a rabbit case study. Linoleic acid (LA) and α-linolenic acid (ALA) are members of two classes of PUFAs, namely the n-6 and n-3 series, which are required for normal human health. Both are considered precursors of a cascade of molecules (eicosanoids), which take part in many biological processes (inflammation, vasoconstriction/vasodilation, thromboregulation, etc.). However, their biological functions are opposite and are mainly related to the form (precursor or long-chain products) in which they were administered and to the enzyme-substrate preference. ALA is widely present in common vegetable oils and foods, marine algae, and natural herbs, whereas its long-chain PUFA derivatives are available mainly in fish and animal product origins. Recent studies have shown that the accumulation of n-3 PUFAs seems mostly to be tissue-dependent and acts in a tissue-selective manner. Furthermore, dietary n-3 PUFAs widely affect the lipid oxidation susceptibility of all tissues. In conclusion, sustainable sources of n-3 PUFAs are limited and exert a different effect about (1) the form in which they are administered, precursor or derivatives; (2) their antioxidant protections; and (3) the purpose to be achieved (health improvement, physiological and reproductive traits, metabolic pathways, etc.).

Indexed as

PUFA metabolismPUFA sourcesrabbitsupplementation

Identifiers

PMID31618904
PMCPMC6827073
OpenAlexW2980349878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.