Evidence map›Paper›PMID 31618867›Full record

ArticleNutrients2019

Prevalence of Medication-Dietary Supplement Combined Use and Associated Factors.

Ignacio Aznar-Lou, Cristina Carbonell-Duacastella, Ana Rodriguez, Inés Mera, Maria Rubio-Valera

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ignacio Aznar-LouTeaching, Research & Innovation Unit, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Parc Sanitari Sant Joan de Déu, 08830 Sant Boi de Llobregat (Barcelona), Spain. i.aznar@pssjd.org.ORCID 0000-0002-6780-5968
Cristina Carbonell-DuacastellaTeaching, Research & Innovation Unit, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Parc Sanitari Sant Joan de Déu, 08830 Sant Boi de Llobregat (Barcelona), Spain. c.carbonell@pssjd.org.ORCID 0000-0002-8794-5490
Ana RodriguezSpanish Society of Community and Family Pharmacy (SEFAC), 28045 Madrid, Spain. ana.rodriguez@sefac.org.
Inés MeraSpanish Society of Community and Family Pharmacy (SEFAC), 28045 Madrid, Spain. ines.mera@hotmail.es.
Maria Rubio-ValeraTeaching, Research & Innovation Unit, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Parc Sanitari Sant Joan de Déu, 08830 Sant Boi de Llobregat (Barcelona), Spain. mrubio@pssjd.org.ORCID 0000-0003-2856-1697
Parc Sanitari Sant Joan de Déu · ESSpanish Society of Family and Community Medicine · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe use of medication has increased in recent years in the US while the use of dietary supplements has remained stable but high. Interactions between these two kinds of products may have important consequences, especially in the case of widely used medications such as antihypertensives and antibiotics. The aim of this paper is to estimate the prevalence of potentially serious drug-dietary supplement interactions among tetracyclines, thiazides, and angiotensin II receptor blocker users by means of the NHANES 2013-2014 dataset.

methodsData from 2013-2014 NHANES were obtained. Potential interactions analysed were tetracyclines with calcium, magnesium, and zinc, thiazides with vitamin D, and angiotensin II receptors blockers with potassium. Prevalence was calculated for each potential interaction. Logistic regression was used to assess associated factors.

results864 prescriptions issued to 820 patients were analysed. Overall prevalence of potential interaction was 49%. Older age and higher educational level were strongly associated with being at risk of a potential interaction. Factors such as age, race, civil status, citizenship, country of birth, BMI, and physical activity did not show notable associations.

conclusionsHealthcare professionals should be aware of other medical products when they prescribe or dispense a medication or a dietary supplement, especially to the older population and people with a higher educational level.

Indexed as

AdultAgedAged, 80 and overAge FactorsAngiotensin Receptor AntagonistsAnti-Bacterial AgentsAntihypertensive AgentsCross-Sectional StudiesDietary SupplementsDrug InteractionsDrug-Related Side Effects and Adverse ReactionsEducational StatusFemaleHumansMaleMiddle AgedAngiotensin Receptor AntagonistsAnti-Bacterial AgentsAntihypertensive AgentsSodium Chloride Symporter InhibitorsTetracyclinesantibioticsantihypertensive medicationdietary supplementsinteractionsprevalence

Identifiers

PMID31618867
PMCPMC6835757
OpenAlexW2981232885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.