Evidence map›Paper›PMID 31618863›Full record

Trial reportNutrients2019

Plasma Free Amino Acid Responses to Whey Protein and Their Relationships with Gastric Emptying, Blood Glucose- and Appetite-Regulatory Hormones and Energy Intake in Lean Healthy Men.

Rachel A Elovaris, Amy T Hutchison, Kylie Lange, Michael Horowitz, Christine Feinle-Bisset, Natalie D Luscombe-Marsh

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Nutrient Combinations Sensed by L-Cell Receptors Potentiate GLP-1 Secretion.International journal of molecular sciences · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Rachel A ElovarisAdelaide Medical School and National Health and Medical Research Council of Australia Centre of Research Excellence in Translating Nutritional Science to Good Health, Adelaide Health and Medical Sciences Building, Corner North Terrace and George Street, Adelaide 5005, Australia. rachel.elovaris@adelaide.edu.au.
Amy T HutchisonAdelaide Medical School and National Health and Medical Research Council of Australia Centre of Research Excellence in Translating Nutritional Science to Good Health, Adelaide Health and Medical Sciences Building, Corner North Terrace and George Street, Adelaide 5005, Australia. amy.hutchison@adelaide.edu.au.ORCID 0000-0002-6393-3671
Kylie LangeAdelaide Medical School and National Health and Medical Research Council of Australia Centre of Research Excellence in Translating Nutritional Science to Good Health, Adelaide Health and Medical Sciences Building, Corner North Terrace and George Street, Adelaide 5005, Australia. kylie.lange@adelaide.edu.au.
Michael HorowitzAdelaide Medical School and National Health and Medical Research Council of Australia Centre of Research Excellence in Translating Nutritional Science to Good Health, Adelaide Health and Medical Sciences Building, Corner North Terrace and George Street, Adelaide 5005, Australia. michael.horowitz@adelaide.edu.au.
Christine Feinle-BissetAdelaide Medical School and National Health and Medical Research Council of Australia Centre of Research Excellence in Translating Nutritional Science to Good Health, Adelaide Health and Medical Sciences Building, Corner North Terrace and George Street, Adelaide 5005, Australia. christine.feinle@adelaide.edu.au.ORCID 0000-0001-6848-0125
Natalie D Luscombe-MarshAdelaide Medical School and National Health and Medical Research Council of Australia Centre of Research Excellence in Translating Nutritional Science to Good Health, Adelaide Health and Medical Sciences Building, Corner North Terrace and George Street, Adelaide 5005, Australia. natalie.luscombe-marsh@csiro.au.
National Health and Medical Research Council · AUCommonwealth Scientific and Industrial Research Organisation · AUSouth Australian Health and Medical Research Institute · AU

Funding

National Health and Medical Research Council 627002, 2019-2015National Health and Medical Research Council 627118, 2010-2014University of Adelaide Postgraduate ScholarshipUniversity of Adelaide Research Training Scholarship
6 · The paper itself

Abstract

This study determined the effects of increasing loads of whey protein on plasma amino acid (AA) concentrations, and their relationships with gastric emptying, blood glucose- and appetite-regulatory hormones, blood glucose and energy intake. Eighteen healthy lean men participated in a double-blinded study, in which they consumed, on 3 separate occasions, in randomised order, 450-mL drinks containing either 30 g (L) or 70 g (H) of pure whey protein isolate, or control with 0 g of protein (C). Gastric emptying, serum concentrations of AAs, ghrelin, cholecystokinin (CCK), glucagon-like-peptide 1 (GLP-1), insulin, glucagon and blood glucose were measured before and after the drinks over 180 min. Then energy intake was quantified. All AAs were increased, and 7/20 AAs were increased more by H than L. Incremental areas under the curve (iAUC

Indexed as

Appetite RegulationEnergy IntakeGastric EmptyingAdolescentAdultAmino AcidsBiomarkersBlood GlucoseCross-Over StudiesDouble-Blind MethodHealthy VolunteersHumansMalePeptide HormonesSouth AustraliaTime FactorsAmino AcidsBiomarkersBlood GlucosePeptide HormonesWhey Proteinsappetite regulationbranched-chain amino acidscholecystokinindairyglucagonglucagon-like peptide-1human

Identifiers

PMID31618863
PMCPMC6835323
OpenAlexW2980955791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.