Evidence map›Paper›PMID 31618826›Full record

ArticleMolecules (Basel, Switzerland)2019

Antimalarial Properties of Dunnione Derivatives as NQO2 Substrates.

Monivan Chhour, Agnès Aubouy, Sandra Bourgeade-Delmas, Pierre Pério, Hélène Ternet-Fontebasso, Mahamane Haidara, Gilles Ferry, Françoise Nepveu, Jean A Boutin, Karine Reybier

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Monivan ChhourUMR 152 Pharma-Dev, Université de Toulouse, IRD, UP 31062 Toulouse, France. monivanc@gmail.com.
Agnès AubouyUMR 152 Pharma-Dev, Université de Toulouse, IRD, UP 31062 Toulouse, France. agnes.aubouy@ird.fr.ORCID 0000-0003-2265-4972
Sandra Bourgeade-DelmasUMR 152 Pharma-Dev, Université de Toulouse, IRD, UP 31062 Toulouse, France. sandra.bourgeade-delmas@ird.fr.
Pierre PérioUMR 152 Pharma-Dev, Université de Toulouse, IRD, UP 31062 Toulouse, France. pierre.perio@univ-tlse3.fr.ORCID 0000-0003-4413-2948
Hélène Ternet-FontebassoUMR 152 Pharma-Dev, Université de Toulouse, IRD, UP 31062 Toulouse, France. helene.ternet-fontebasso@univ-tlse3.fr.
Mahamane HaidaraUMR 152 Pharma-Dev, Université de Toulouse, IRD, UP 31062 Toulouse, France. mahamanehaidara83@gmail.com.
Gilles FerryPôle d'Expertise Biotechnologie, Chimie, Biologie, Institut de Recherches Servier, 125, Chemin de Ronde, 78290 Croissy sur Seine, France. gilles.ferry@servier.com.
Françoise NepveuUMR 152 Pharma-Dev, Université de Toulouse, IRD, UP 31062 Toulouse, France. francoise.nepveu@fondationpierrefabre.org.
Jean A BoutinPôle d'Expertise Biotechnologie, Chimie, Biologie, Institut de Recherches Servier, 125, Chemin de Ronde, 78290 Croissy sur Seine, France. jean.boutin@servier.com.ORCID 0000-0003-0068-7204
Karine ReybierUMR 152 Pharma-Dev, Université de Toulouse, IRD, UP 31062 Toulouse, France. karine.reybier-vuattoux@univ-tlse3.fr.
Université Fédérale de Toulouse Midi-Pyrénées · FRPlateforme Technologique d'Innovation Biomédicale · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dunnione, a natural product isolated from the leaves of

Indexed as

AnimalsAntimalarialsDisease Models, AnimalHeLa CellsHumansMiceMolecular StructureNaphthoquinonesQuinone ReductasesReactive Oxygen SpeciesStructure-Activity RelationshipSubstrate SpecificityAntimalarialsdunnioneNaphthoquinonesNRH - quinone oxidoreductase2Quinone ReductasesReactive Oxygen Speciesdunnione analoguesin vivo efficacymalariaPlasmodium spp., drug discovery

Identifiers

PMID31618826
PMCPMC6832513
OpenAlexW2979374824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.