Evidence map›Paper›PMID 31618814›Full record

ArticleInternational journal of environmental research and public health2019

Blending Insights from Implementation Science and the Social Sciences to Mitigate Inequities in Screening for Hereditary Cancer Syndromes.

Laura Senier, Colleen M McBride, Alex T Ramsey, Vence L Bonham, David A Chambers

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Laura SenierDepartment of Sociology & Anthropology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA. l.senier@northeastern.edu.
Colleen M McBrideDepartment of Behavioral Sciences & Health Education, Rollins School of Public Health, Emory University, 1518 Clifton Road NE, Atlanta, GA 30322, USA. colleen.marie.mcbride@emory.edu.
Alex T RamseyDepartment of Psychiatry, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA. aramsey@wustl.edu.
Vence L BonhamSocial and Behavioral Research Branch, National Human Genome Research Institute, National Institutes of Health, 31 Center Drive, Bethesda, MD 20892, USA. bonhamv@mail.nih.gov.
David A ChambersDivision of Cancer Control and Population Sciences, National Cancer Institute, 9609 Medical Center Drive, Rockville, MD 20850, USA. dchamber@mail.nih.gov.

Funding

Washington University Career Development Program in Drug Abuse and AddictionK12DA041449 · NIDA · WASHINGTON UNIVERSITY · PI Laura J. Bierut, Patricia A Cavazos-Rehg · 2017 to 2026
$4.2M
Barriers in Translating Genomic Research into State Public Health ProgramsK01HG006441 · NHGRI · UNIVERSITY OF WISCONSIN-MADISON · PI SENIER, LAURA · 2012 to 2016
$885k
NHGRI NIH HHS 1K01HG006441-01A1NIDA NIH HHS K12 DA041449NIH HHS K12DA041449
6 · The paper itself

Abstract

Genomic screening to identify people at high risk for adult-onset hereditary conditions has potential to improve population health. However, if not equitably accessible, genomics-informed screening programs will exacerbate existing health inequities or give rise to new ones. To realize the disease prevention potential of these screening tools, we need strategies to broaden their reach. We propose a conceptual framework that merges insights from implementation science and sociological research on health inequities. Our framework does three things: first, it broadens the arenas of action beyond those typically addressed in implementation science frameworks; second, it argues for recruiting more diverse partners to share the work of implementation and dissemination; and third, it shows how implementation activities can be coordinated more effectively among those partners. We use screening for hereditary breast and ovarian cancers (HBOC) as a case to illustrate how this enhanced framework could guide implementation science and distribute the benefits of genomic medicine more equitably. Although our example is specific to genomics, this approach is more broadly applicable to the field of implementation science. Coordinated action among multiple stakeholders could translate a host of new technologies from the bench to the trench without creating new inequities or exacerbating existing ones.

Indexed as

Implementation ScienceBreast NeoplasmsEarly Detection of CancerHumansNeoplastic Syndromes, Hereditaryconsolidated framework for implementation researchgenomicshealth inequitiespublic health

Identifiers

PMID31618814
PMCPMC6843353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.