Evidence map›Paper›PMID 31618759›Full record

ArticleNature2019

Concise asymmetric synthesis of (-)-bilobalide.

Meghan A Baker, Robert M Demoret, Masaki Ohtawa, Ryan A Shenvi

Abstract read
In one paragraph

Article in Nature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Neurotrophic Natural Products.Progress in the chemistry of organic natural products · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Recent progress in alkynylation with hypervalent iodine reagents.Chemical communications (Cambridge, England) · 2023
    Review
  10. Molecules (Basel, Switzerland) · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Fe-Catalyzed Anaerobic Mukaiyama-Type Hydration of Alkenes using Nitroarenes.Angewandte Chemie (International ed. in English) · 2021
    Article
  16. Review
  17. Review
  18. Review
  19. Synthetic, Mechanistic, and Biological Interrogation ofJournal of the American Chemical Society · 2020
    Article
  20. Synthesis of (-)-Picrotoxinin by Late-Stage Strong Bond Activation.Journal of the American Chemical Society · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Meghan A Baker *Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Robert M Demoret *Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Masaki OhtawaDepartment of Chemistry, The Scripps Research Institute, La Jolla, CA, USA. ohtawam@pharm.kitasato-u.ac.jp.
Ryan A ShenviDepartment of Chemistry, The Scripps Research Institute, La Jolla, CA, USA. rshenvi@scripps.edu.
Scripps Research Institute · US

Funding

Unusual Pharmacophores and New Tools for Cross-CouplingR35GM122606 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI Ryan Ashok Shenvi · 2017 to 2026
$7.1M
NIGMS NIH HHS R35 GM122606
6 · The paper itself

Abstract

The Ginkgo biloba metabolite bilobalide is widely ingested by humans but its effect on the mammalian central nervous system is not fully understood

Indexed as

Chemistry Techniques, AnalyticalCyclopentanesFuransGinkgo bilobaGinkgolidesOxidation-ReductionbilobalideCyclopentanesFuransGinkgolides

Identifiers

PMID31618759
PMCPMC7017908
OpenAlexW2980447845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.