Evidence map›Paper›PMID 31618696›Full record

ArticleJournal of cardiac failure2020

Impact of Obesity on Ventricular Assist Device Outcomes.

Abhishek Jaiswal, Lauren K Truby, Astha Chichra, Rashmi Jain, Leann Myers, Nirav Patel, Veli K Topkara

Open access · greenAbstract read
In one paragraph

Article in Journal of cardiac failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. The impact of position changes of the inflow cannula in LVAD patients.Turk gogus kalp damar cerrahisi dergisi · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. The Impact of Obesity on Cardiovascular Diseases: Heart Failure.Methodist DeBakey cardiovascular journal · 2025
    Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Mitigating Racial Bias in Machine Learning.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2022
    Article
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Abhishek JaiswalHartford HealthCare Heart and Vascular Institute, Hartford, Connecticut. Electronic address: abhishek.jaiswal@hhchealth.org.
Lauren K TrubyDivision of Cardiology, Columbia University College of Physicians and Surgeons, New York, New York.
Astha ChichraDivision of Pulmonary and Critical Care, Department of Medicine, Yale School of Medicine, New Haven, Connecticut.
Rashmi JainDivision of Cardiology, Columbia University College of Physicians and Surgeons, New York, New York.
Leann MyersDepartment of Global Biostatistics and Data Science, Tulane School of Public Health, New Orleans, Louisiana.
Nirav PatelHartford HealthCare Heart and Vascular Institute, Hartford, Connecticut.
Veli K TopkaraDivision of Cardiology, Columbia University College of Physicians and Surgeons, New York, New York.
Columbia University · USHartford Hospital · USTulane University · USYale University · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI JUDD E SHELLITO · 2012 to 2026
$69.1M
NHLBI NIH HHS HHSN268201100025CNIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

backgroundObesity remains a relative contraindication for heart transplantation, and hence, obese patients with advanced heart failure receive ventricular assist devices (VADs) either as a destination or "bridge to weight loss" strategy. However, impact of obesity on clinical outcomes after VAD implantation is largely unknown. We sought to determine the clinical outcomes of obese patients with body mass index (BMI) ≥ 35 kg/m

methodsThe Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) registry was queried for patients who underwent VAD implantation. Patients were categorized into BMI groups based on World Health Organization classification.

resultsOf 17,095 patients, 2620 (15%) had a BMI ≥ 35 kg/m

conclusionsObesity alone should not be considered a contraindication for VAD therapy in contemporary era. Given durability of heart transplantation, strategies should be developed to promote weight loss, which occurs infrequently in obese patients. Impact of weight loss on clinical outcome of obese patients warrants further investigation.

Indexed as

Heart-Assist DevicesHeart FailureHeart TransplantationFemaleHumansObesityRegistriesRetrospective StudiesTreatment Outcomebleedingdevice malfunctiondevice thrombosisobesityVentricular assist deviceweight loss

Identifiers

PMID31618696
PMCPMC7141964
OpenAlexW2979514211

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.